ELIOS online referral and support for young people with suicidal thoughts
Official title: Online Referral and Intervention to Prevent Adolescent and Young Adult Suicide
Run by University Hospital, Lille · NCT04642157 · Data updated 2026-11-12
This project will test whether ELIOS, an online web-clinician contact system, can reduce suicidal thoughts in French adolescents and young adults who seek help online.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 25 Years |
| Sex | All |
| Enrollment | 396 (estimated) |
| Sponsor | University Hospital, Lille Academic / other |
| Locations | 1 site (Lille) |
| Status | Recruiting |
| Started | October 13, 2022 |
| Main results expected | July 13, 2026 |
| Study ends | July 13, 2026 |
| Registry record updated | June 27, 2025 |
| Trial ID | NCT04642157 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are French-speaking adolescents and young adults (no minors) up to about age 25 who have experienced suicidal ideation within the week before contacting the service and who can access social media or web channels.
✕Probably not a fit
People contacting on behalf of someone else, non-French speakers, those living outside France, and minors are not eligible and therefore will not benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
ORIAS is a randomized controlled trial comparing the ELIOS digital outreach and intervention system to standard online professional contact among adolescents and young adults in France who reach out for suicidal ideation. Participants randomized to ELIOS receive proactive contacts and short-term counseling from trained web-clinicians (psychologists and nurses supervised by psychiatrists) via social media and other online channels, with scheduled recontacts at 24 hours, 72 hours and 7 days as needed. The control arm receives the same generic mental health resources and professional contact information but not the ELIOS protocol. The primary outcome is change in suicidality at three months, with additional measures of help-seeking motivation and linkage to care.
Why it matters
Potential benefit: If successful, ELIOS could reduce suicidal thoughts and increase timely connection to care for distressed young people who seek help online.
How similar studies have gone: Internet-based suicide prevention trials are limited and randomized evidence is scarce, so ELIOS represents a novel, relatively untested approach tailored to social media interaction.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * To spontaneously contact the ELIOS online system * To have been experiencing suicidal ideations in the week prior the contact * To live in France and speak French * To provide informed consent For ethical reasons, we decided not to include minors, due to impossibility of getting the parental authorizations without compromising the facilitation role of the system. However, most recent expert consensus consider that adolescence extends to 25 years old. Exclusion Criteria: * To contact the ELIOS online system for a relative or an acquaintance
Where it's running
-
CHU de Lille
Lille, France Recruiting
Study contacts
- Principal investigator: Charles-Edouard Notredame, MD — CHU Lille
- Study coordinator: Charles-Edouard Notredame, MD
- Email: charles-edouard.notredame@chru-lille.fr
- Phone: 3 20 44 67 47
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.