Brief Skills for Safer Living: one-session therapy for people with suicidal thoughts

Investigating the Efficacy of a Novel Therapy for Suicide Risk in Adults: A Randomized Controlled Trial of an Intensive Single Session of "Brief Skills for Safer Living"

Not applicable Interventional Unity Health Toronto · NCT06571916

This trial will test whether one brief, virtual Brief-SfSL session plus usual care helps adults in Canada with recent suicidal thoughts reduce suicidal thinking compared with usual care alone.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment150 (estimated)
Ages18 Years and up
SexAll
SponsorUnity Health Toronto Academic / other
Locations1 site (Toronto, Ontario)
Trial IDNCT06571916 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial will enroll 150 adults across Canada who have had suicidal thoughts in the past week and randomize them to receive either a single-session Brief-SfSL intervention plus treatment as usual or treatment as usual with a 3-month waitlist for Brief-SfSL. Brief-SfSL is a one-session, individually delivered psychotherapy adapted from a longer 20-week group program and is delivered virtually. Primary outcomes include changes in suicidal ideation at 3 months, with secondary measures of depression, anxiety, anhedonia, social connectedness, emotion regulation, functioning, executive control, and social problem-solving, and monitoring of adverse events. The design builds on a prior single-arm pilot of 77 adults showing feasibility and safety and compares Brief-SfSL against treatment as usual to determine efficacy.

Who should consider this trial

Good fit: Ideal candidates are adults in Canada with suicidal ideation in the past week who can use a phone or computer with internet, can consent in English, have an emergency contact and local hospital access, and are not currently receiving another psychotherapy.

Not a fit: Patients with active psychosis, significant cognitive impairment, inability to participate in English, or those who require more intensive or ongoing psychotherapeutic care may not benefit from this single-session intervention.

Why it matters

Potential benefit: If successful, it could offer a fast, widely accessible single-session therapy that reduces suicidal thoughts and improves coping for people at risk.

How similar studies have performed: A prior single-arm virtual pilot of Brief-SfSL in 77 Canadian adults showed feasibility, acceptability, safety, and signals of reduced suicidal risk, and the approach is adapted from a previously successful 20-week group program.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Suicidal ideation in the past week
* Access to a computer or phone with a camera
* Access to internet
* Access to an emergency contact and hospital within commuting distance
* Not receiving other psychotherapy/counselling services concurrently
* Willing to have the session recorded to determine therapy fidelity
* Any psychiatric diagnosis is allowed
* Follow-up visits with a psychiatrist and/or family doctor where a psychotherapeutic modality (e.g., Dialectical Behavioural Therapy, psychodynamic therapy, etc.) is not being used are allowable

Exclusion Criteria:

* Inability to undergo psychotherapy in English
* Presence of cognitive impairment that would limit consent and understanding of Brief Skills for Safer Living
* Active psychosis
* Unwilling or unable to provide informed consent
* Previously enrolled in the Brief-SfSL pilot study
* Unwilling or unable to communicate verbally

Where this trial is running

Toronto, Ontario

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Suicide PreventionSuicideSuicide and Self-harmsuicidepsychotherapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.