NIH-funded research R01 grant

Scaling Out S.A.F.E. Firearm Across Two Health Systems as a Universal Suicide Prevention Strategy

Funded at Northwestern University · NIH-11480141 · Data updated 2026-11-12

A proven firearm-safety intervention used during well-child and adult visits would be expanded across two large health systems to help prevent suicide.

More Suicide research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University
NIH-funded
Lab location1 site (Chicago, United States)
Project startJanuary 16, 2025
Project endOctober 31, 2029
Funding year2027
Award (this year)$713,197
NIH project number5R01MH138333-03
Project IDNIH-11480141 on NIH RePORTER

Who could benefit from this research

Could help

Patients receiving care in pediatric, adult primary care, or women’s health clinics at participating health systems who may benefit from firearm-safety guidance and access to the S.A.F.E. Firearm intervention.

Less likely to help

Patients not engaging with the intervention or those in non-participating clinics may see no direct benefit.

What this research studies

This project builds on the ASPIRE trial to spread a universal firearm-safety intervention into adult primary care and women’s health clinics, aiming to reach broad patient populations. It tests implementation strategies like clinician prompts in electronic health records and dedicated support to clinics to achieve higher adoption. The study involves training providers, integrating decision-support tools, and providing facilitation to clinics to sustain the program across pediatric, adult, and women’s health settings. The goal is to reduce suicide risk by safely managing access to firearms in homes where patients live and may have children or other high-risk factors.

Why it matters

Potential benefit: If successful, patients and families could experience fewer firearm-related suicides through easier access to prevention tools and guidance during routine care.

How similar studies have gone: Previous ASPIRE results showed substantial improvement in reach from 3% to 54% with a combination of training, EHR prompts, and implementation support.

Where this research is happening

  • Northwestern University
    Chicago, United States
    Active

Researchers

  • Principal investigator: Beidas, Rinad Sary — Northwestern University
  • Study coordinator: Beidas, Rinad Sary

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.