Uncovering the genetics and biology of suicide outcomes
Official title: Establishing the Suicide Working Group of the Psychiatric Genomics Consortium to elucidate the genetics and biology of suicide outcomes
Funded at Icahn School of Medicine at Mount Sinai · NIH-11494290 · Data updated 2026-11-12
Researchers are studying the genetic and biological factors behind suicide outcomes to better understand why they occur and how they relate to mental health conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | December 6, 2023 |
| Project end | October 31, 2028 |
| Funding year | 2027 |
| Award (this year) | $828,058 |
| NIH project number | 5R01MH132733-04 |
| Project ID | NIH-11494290 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with a history of suicidal thoughts, attempts, or suicide attempters who might benefit from future targeted interventions.
✕Less likely to help
People without a genetic predisposition or those not matching study populations may not directly benefit.
What this research studies
This project brings together large international datasets to study the genetics of suicide outcomes across diverse populations. By analyzing genome-wide data from thousands of cases of suicide attempts, suicides, and suicidal thoughts, the team aims to identify genetic factors that contribute to risk. The goal is to reveal biological pathways that could lead to new prevention and treatment strategies, while considering how these factors intersect with other psychiatric conditions. The work will involve collaboration across clinical, population, and medical examiner resources to build a comprehensive picture of suicide risk at the molecular level.
Why it matters
Potential benefit: If successful, this work could point to new targets for prevention and therapies that reduce suicide risk.
How similar studies have gone: Previous large-scale genetic studies have identified some factors, but a full spectrum analysis across SA, SD, and SI is still emerging.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Mullins, Niamh — Icahn School of Medicine at Mount Sinai
- Study coordinator: Mullins, Niamh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.