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Suicide Prevention clinical trials and research
As of November 12, 2026, Find a Trial lists 33 Suicide Prevention clinical trials that are recruiting, at sites in 11 countries (most in United States (18), Belgium (5), Canada (2)). 2 were first registered in the last 30 days. By phase: Phase 4 (1). The most active sponsors are University Ghent (5), VA Office of Research and Development (3), University of Washington (2). There are also 98 NIH-funded research projects on Suicide Prevention, with $54.8 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 33Clinical trials
- 98NIH research projects
- 2New in 30 days
- 11Countries
Newest Suicide Prevention clinical trials
All recruiting trials (33)
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How TikTok Trigger Warnings affect at-risk youth
This study tests whether TikTok trigger warnings change how young people at risk of suicide feel and behave when they see suicide-related content.
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Multi-layered digital monitoring and pharmacogenomics to prevent suicide in adults with depression
This study tests whether a digital monitoring system, a digital safety plan, and pharmacogenetic-guided care can reduce suicide re-attempts in adults with depression.
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Combining the Youth-Nominated Support Team with CBT for Black adolescents at acute suicide risk
This project will test whether adding a computer-assisted Youth-Nominated Support Team to Cognitive Behavioral Therapy for Suicide Prevention helps Black adolescents (ages 12-17) who come to an urban emergency setting with suicidal thoughts or self-injury.
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Online suicide prevention and intervention training for secondary school counselors
This tests an online suicide prevention and intervention training program for secondary school counselors to see if it improves their knowledge, confidence, attitudes, and reduces stigma about suicidal behavior.
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HAVEN-Connect: Church-based suicide prevention for Black youth
This project will test whether HAVEN-Connect, a church-centered program, can reduce depression and suicide risk in Black adolescents aged 13–19.
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Life skills training for Soldiers at their first duty station
This project tests whether a mobile-delivered, military-tailored life skills program called Level Up can help Soldiers arriving at their first duty station reduce suicidal and other harmful behaviors and improve mental health.
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Co-creating suicide prevention tools for people in prison
This project will work with people in prison and prison care staff to test and adapt three suicide prevention tools so they fit prison life and are easier to use.
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Youth suicide risk factors and personalized reduction strategies in young adults
This study tests whether combining clinical data, genetic information, neuroimaging, and microbiome data can help identify risk factors and see if a dTMS-based intervention reduces suicide risk in young adults with mood disorders.
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Chat conversations with the suicide helpline 1813: how people experience them
This study tests how people feel before and after chatting with the Zelfmoordlijn 1813 helpline to see if the chat affects suicidal thoughts or feelings.
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Esketamine or Crisis Planning Added to Usual Care for Suicidality in Brazil
This trial tests whether a single esketamine infusion or a single Crisis Response Planning session, added to enhanced treatment as usual, can reduce future suicide-related events in adolescents and adults in Indaiatuba, Brazil.
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Combined peer support, personalized Hope Box, and postcard follow-up for suicidal inpatients
This project will try a combined program of a peer helper meeting, a personalized Hope Box, and a reminder postcard to help people hospitalized after a recent suicide attempt.
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E-learning suicide prevention training for prison staff in Belgian detention centers
This project will test whether an online gatekeeper training helps prison staff in Belgium feel more confident and knowledgeable about preventing suicide among people in detention.
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User feedback on Zelfmoord1813.be and related websites
This project tests how easy and helpful the Zelfmoord1813.be and related suicide-prevention websites are for people aged 16 and older who have visited them.
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Caring Contacts via Text Messages for suicidal adolescents after emergency department discharge
This study tests whether brief, hopeful text messages can help adolescents with suicidal thoughts or behaviors after leaving the emergency department, alongside usual care.
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Bridge the Gap (BTG) — group program for Black adolescents at risk for suicide
This project tests a 10-week, culturally adapted CAMS-based group program to see if it reduces suicidal thoughts and behavior and increases hope, ethnic identity, and social support for Black youth ages 12–17.
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Counseling intervention to improve firearm storage for those with PTSD
This study is testing a counseling program to see if it can help people with PTSD store their firearms more safely to reduce the risk of suicide.
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Evaluating a suicide risk screening program in rural schools
This study is testing a new program in rural West Virginia schools to see if it can help identify and support students at risk of suicide.
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Creating tools for children and adolescents with suicidal thoughts and behaviors
This study is trying to create helpful tools and a self-help app for kids and teens who have thoughts of suicide, by working with them to better understand their feelings and support needs.
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Coaching to help pediatric clinics use a youth suicide prevention pathway
This project tests whether adding ongoing coaching to NIMH pathway training helps primary care teams better find and manage suicide risk in patients aged 12–24 who screen positive.
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Preventing suicide after discharge from community mental health care
This project will try the VA Brief Intervention and Contact Program (VA BIC) to see if it reduces suicidal thoughts and behaviors and improves care engagement for Veterans after discharge from non-VA acute psychiatric treatment.
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Brief Skills for Safer Living: one-session therapy for people with suicidal thoughts
This trial will test whether one brief, virtual Brief-SfSL session plus usual care helps adults in Canada with recent suicidal thoughts reduce suicidal thinking compared with usual care alone.
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Interactive intervention for safe firearm storage to prevent youth suicide
This study is testing a new program to help parents safely store firearms at home to prevent youth suicide among teenagers who have recently left psychiatric hospitals.
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Evaluating a prevention program for suicidal behavior in at-risk adolescents
This study is testing a new program to help prevent suicidal thoughts and behaviors in at-risk teenagers, including those in detention or facing mental health challenges, to see if it works better than an art-based activity.
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Connecting jail release data with health records for suicide prevention
This study is testing if linking jail release records with health records can help people get better mental health support after leaving jail to prevent suicide.
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Adapting a brief suicide intervention for teens in pediatric primary care
This project tests a teen-focused suicide-prevention program in three pediatric clinics to see if it’s acceptable, feasible, and may reduce suicide risk compared with usual care.
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Psychoeducational course aimed at preventing suicide
This study tests whether a new psychoeducational course can help people who have had thoughts of suicide learn to manage their feelings and create a safety plan better than standard individual sessions.
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Safety planning and transdiagnostic CBT to prevent suicide in Mozambican teens
This project tests whether safety planning and a transdiagnostic cognitive behavioral program can reduce suicidal thoughts and behaviors in secondary school students in Mozambique.
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Using a smartphone app to help prevent suicide in veterans after hospital discharge
This study is testing a smartphone app designed to help prevent suicide in veterans after they leave the hospital by providing support and resources to manage their mental health.
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Caring Connections: youth suicide detection and support
This pilot will test whether Caring Connections, a culturally adapted 90-day care coordination program delivered through community and faith-based hubs, helps high-risk Black and other youth aged 13–19 reduce suicidal thoughts and connect with mental health services.
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Preventing suicidal behavior in high-risk youth in emergency care settings
This study is testing two different short interventions to see which one better helps young people aged 12-19 who are at risk of suicide when they come to the emergency room.
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A program to reduce suicide risk in primary care for adolescents
This study is testing a new program to see if it can help reduce the risk of suicide in teenagers aged 12-17 who visit their primary care doctors.
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Workshop to help recently transitioned Veterans reduce suicide risk and improve reintegration
This study is testing a workshop designed to help Veterans transitioning to civilian life reduce their risk of suicide and improve their reintegration by teaching them practical skills and providing support.
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Preventing suicide in homeless youth who use substances
This study is trying out a new therapy combined with regular support to see if it can help homeless young people who use drugs and have thoughts of suicide feel better and stay safe.
NIH-funded research (newest 40 of 98)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Mobile safety planning for at-risk young adults
A digital, text-based safety planning program for young adults (ages 18–24) to help prevent suicide and stay connected to support.
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INCLUSAVE: helping young adults with IDD access suicide-prevention trainings
A new NIH grant studies whether two proven gatekeeper trainings (ASIST and safeTALK) can be delivered in inclusive settings to support young adults with intellectual and developmental disabilities and their communities.
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Technology-assisted suicide prevention for youth in Colombian school settings
A youth-focused program will test a culturally tailored digital platform and teacher training to reduce suicidal thoughts and behaviors in schools.
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Qnnections: A Social Connection‑Focused Suicide Prevention for LGBTQ+ Veterans
A new group-based program tailored for LGBTQ+ Veterans aims to strengthen belonging and reduce burdensomeness to help prevent suicide.
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Nurse- and Peer-Led Suicide Prevention for Women in Tajikistan
A nurse- and peer-led program in Tajikistan aims to help women at risk of suicide by adding tailored, frontline support in primary care.
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Targeted online suicide prevention for Veterans
A web-based, one-session intervention for Veterans to reduce thoughts of suicide and self-harm by helping them manage distress and rigid thinking.
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Telehealth support to prevent suicide in people with alcohol use disorder in Tanzania
A telehealth counseling program is being adapted to help reduce suicide risk for people with alcohol use disorder in emergency departments in Tanzania.
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Suicide prevention support in rural Nepal primary care
This project brings practical suicide-prevention supports to primary care clinics and community health workers in rural Nepal to help people who are at risk.
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Scaling Out S.A.F.E. Firearm Across Two Health Systems as a Universal Suicide Prevention Strategy
A proven firearm-safety intervention used during well-child and adult visits would be expanded across two large health systems to help prevent suicide.
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Suicide prevention using safety plans and cognitive behavioral therapy for adolescents in Mozambique
Young people in Mozambican secondary schools will receive safety planning and cognitive behavioral therapy from trained non-specialists to help reduce suicidal thoughts and behaviors.
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THRIVE: a recovery-focused suicide prevention program for crisis stabilization centers
A multi-site plan tests a brief recovery-oriented therapy and post-discharge coaching to reduce suicide risk for adults treated in crisis stabilization centers.
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INSPIRE: Innovations in Suicide Prevention Research
Aims to improve suicide prevention by creating linked data systems and benchmarks to help insurers, health systems, and correctional departments monitor and prevent suicides.
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Center to speed up real-world youth suicide prevention
A nationwide effort to put proven youth suicide prevention strategies into everyday health care so that at-risk kids get help faster.
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Coordinating Suicide Prevention Across Jails and Community Health
A large national effort to better identify and connect people at risk of suicide who touch both jail systems and community healthcare to get faster, safer care.
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Centering suicide prevention at the intersection of health and criminal-legal systems
A large NIH-funded center is testing how data from police and court interactions can help identify people at risk of suicide and connect them with care.
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Technology-assisted suicide prevention for youth in Colombian schools
A youth-focused, culturally tailored program uses digital tools and teacher training to reduce suicidal thoughts and behaviors among adolescents in schools.
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Strengths-based suicide prevention for Black sexual minority youth
A research project aims to help Black sexual minority youth reduce suicidal thoughts and behaviors by understanding protective factors and risks in everyday life.
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Pilot implementation of the WHO LIVE LIFE guide for suicide prevention in Uganda
A small, real-world test in rural Uganda to see if the WHO LIVE LIFE guide, led by district health teams, helps communities prevent suicide.
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Nurse- and Peer-Led Suicide Prevention in Tajikistan
A new program in Tajikistan would test a nurse- and peer-led approach to preventing suicide among women at risk, delivered through primary care clinics.
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Together We Can: a multi-level suicide prevention program for teens, teachers, and caregivers
A new program for 12–19 year-olds, their teachers, and caregivers to reduce suicide risk through school-based activities, expanded mental health literacy, and guided help-seeking.
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Culturally-appropriate tech tools to prevent suicide among Colombian schoolchildren
This project brings culturally-adapted apps and teacher training into Colombian schools to help reduce suicidal thoughts and support youth mental health.
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Nurse and Peer Support to Prevent Suicide for Women in Tajikistan
This project offers a nurse- and peer-led program to help adult women in Tajikistan at moderate or high risk of suicide stay safer and improve their mental health.
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Socioecological factors linked to autism and suicide risk in youth
A large study will look at how personal, community, and system factors influence suicide risk and mental health care for autistic teens and young people.
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Using strengths to prevent suicide in Black sexual minority youth
This project uses personal and community strengths plus daily tracking to help reduce suicidal thoughts in Black sexual minority youth ages 13–26.
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Lithium in Alaska Native communities: a hopeful look at suicide prevention
A community-focused study will look at lithium levels in water and traditional foods and test whether low lithium intake relates to suicidality, with a first-of-its-kind low-dose lithium supplementation trial in Northwest Arctic Alaska Native communities.
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Confidential teen suicide prevention in primary care across 30 clinics
A nationwide health system is testing a confidential, teen-friendly suicide prevention approach in 30 primary care clinics to help prevent teen suicidality.
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Quality measures to improve suicide prevention across health systems
Aimed at creating and testing practical measures to track and improve suicide prevention care within US health systems.
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Recovery-oriented peer-led suicide prevention for people at high risk of psychosis
A peer-supported program called RISE is being refined and tested to help people at high risk for psychosis stay engaged in care and reduce thoughts of suicide.
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Prazosin for Suicide Prevention using Large-Scale Health Data
A large VA-backed study will look at whether the blood pressure medicine prazosin could help prevent suicide and self-harm by analyzing real-world health data.
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Suicide prevention for homeless youth who use substances
A program tests a cognitive-therapy based approach to prevent suicide among homeless youth who use drugs or alcohol.
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Innovation in Suicide Prevention for Youth and Young Adults
A center from the University of Pennsylvania aims to improve how proven suicide-prevention practices reach teens and young adults, using new tools to make them work in real-world settings.
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Teens’ confidential suicide prevention in primary care
A nationwide program in 30 primary care clinics tests whether confidential teen suicide prevention tools in routine visits reduce suicidal outcomes and improve care.
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Coaching pediatric clinics to use a youth suicide-prevention pathway
This project offers practice coaching to pediatric primary care clinics so they can better use a youth suicide-prevention pathway for their patients.
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Suicide prevention help for Veterans using VA community care
A program called VA BIC aims to reduce suicide risk among Veterans who receive mental health care outside VA facilities, by providing brief interventions and follow-up contact.
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Integrating suicide prevention into community mental health programs for mothers in low-resource areas
This study is all about helping mothers during pregnancy and after childbirth by making sure they get the mental health support they need, especially to prevent suicidal thoughts, by training community members to recognize and help with these feelings.
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Bringing suicide prevention into local primary health care in rural Nepal
This project builds and pilots simple tools to help local primary care teams and community health workers in rural Nepal find and support people at risk of suicide.
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Safety planning and talk therapy to help Mozambican teenagers at risk of suicide
This project offers safety plans and a short, skills-based cognitive behavioral therapy to help secondary-school students in Mozambique who have suicidal thoughts or behaviors.
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S.A.F.E. Firearm program to promote safer gun storage for adults and families
This project brings the S.A.F.E. Firearm program into adult primary care and women's health clinics to help adults and families store firearms more safely and lower suicide risk.
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VA virtual mental health care and suicide prevention
This project will use VA health records and new analysis methods to find out whether virtual mental health services help prevent suicide and reach underserved Veterans.
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Making short coping plans more helpful using phones and wearables
Researchers will use phone check-ins and wearable sensors to learn when brief safety plans help people recently discharged from psychiatric hospitals who are at high risk for suicide.
Related topics
Quick answers
How many Suicide Prevention clinical trials are recruiting right now?
33, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 11 countries. The most sites are in United States (18 trials), Belgium (5 trials), Canada (2 trials), Brazil (1 trial), Mozambique (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.