Condition

Stroke Rehabilitation clinical trials and research

• 15Clinical trials
• 19NIH research projects
• 8Countries

Newest Stroke Rehabilitation clinical trials

All recruiting trials (15)

• NDT vs. Mirror Therapy for lower limb recovery after sub-acute stroke

  This trial tests whether neurodevelopmental technique (NDT) or mirror therapy (MT) helps improve leg coordination and walking in people 45–65 with sub-acute stroke.

  Recruiting University of Lahore · Lahore, Punjab Province · NCT07742020

• Home-based vs. in-clinic upper extremity rehabilitation after stroke

  This study tests whether a 20-hour home telerehabilitation program (tele-CPASS) works as well as the same in-clinic CPASS therapy for improving arm and hand function after stroke.

  Recruiting at 3 sites University of Texas, El Paso · El Paso, Texas and 2 other locations · NCT07661849

• Balance and fall risk after stroke: Sensorimotor training versus whole-body vibration

  A randomized study tests whether lower-limb sensorimotor training or whole-body vibration can improve balance and reduce fear of falling for people who have had a stroke.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT07642154

• Cerebello-spinal direct current stimulation to improve walking in chronic stroke

  Test whether cerebello-spinal direct current stimulation combined with daily treadmill training improves walking and mobility in people who had a stroke at least six months ago.

  Recruiting at 3 sites Phase 2 Universidade Federal de Pernambuco · João Pessoa, Paraíba and 2 other locations · NCT07073287

• Brain pathways that support arm recovery after stroke

  This trial will try 30 hours (over 6 weeks) of targeted Arm Basis Training versus usual care to see if it improves proximal arm motor control in people 3–6 months after a first ischemic or hemorrhagic stroke with moderate to severe arm impairment.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT06998485

• Curved walking paired with a second task to aid stroke recovery

  This will test whether practicing curved walking while doing a simple mental task helps thinking and walking for people recovering from a first-time stroke.

  Recruiting Fooyin University · Kaohsiung City · NCT06898073

• Digital rehabilitation system for stroke recovery

  This study is testing a smartphone app that uses virtual and augmented reality to help stroke patients recover at home and see if it works better than regular therapy.

  Recruiting at 2 sites Eodyne Systems SL · Cluj-Napoca and 1 other locations · NCT06885502

• Music therapy for stroke rehabilitation in patients with non-fluent aphasia

  This study is trying out a new music therapy for stroke patients with speech difficulties to see if it helps them recover their ability to speak better than regular speech therapy.

  Recruiting at 3 sites All India Institute of Medical Sciences · Delhi, National Capital Territory of Delhi and 2 other locations · NCT06323330

• Predicting stroke rehabilitation outcomes with exercise

  This study is testing if certain tests can help figure out which stroke survivors with leg disabilities will benefit from a special exercise program to improve their walking and overall function.

  Recruiting VA Office of Research and Development · Decatur, Georgia · NCT06059872

• Combining mirror therapy and augmented reality for stroke rehabilitation

  This study tests whether using a combination of mirror therapy and augmented reality can help people who have had a stroke recover better and faster.

  Recruiting at 5 sites National Taiwan University Hospital · New Taipei City and 4 other locations · NCT05993091

• Local vibrations to improve recovery in stroke patients

  This study is testing if adding local vibrations to regular rehab can help stroke patients recover their walking speed better than rehab alone.

  Recruiting at 2 sites Centre Hospitalier Universitaire de Saint Etienne · Le Chambon-Feugerolles and 6 other locations · NCT05945212

• Early rehabilitation using EEG neurofeedback for stroke recovery

  This study tests if using brainwave feedback along with regular rehab can help stroke patients recover better use of their arms.

  Recruiting Rennes University Hospital · Rennes · NCT05884762

• Comparing two robotic therapy methods with exergaming for stroke rehabilitation

  This study is testing two different robotic therapy methods combined with fun video game exercises to see which one helps stroke patients recover better and improve their daily activities.

  Recruiting at 4 sites Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation · Taichung and 3 other locations · NCT05492175

• Using mirror therapy and augmented reality for stroke rehabilitation

  This study is testing if combining mirror therapy with augmented reality can help stroke patients recover better during a 9-week program at home and in clinics.

  Recruiting at 5 sites National Taiwan University Hospital · New Taipei City and 4 other locations · NCT05467813

• Telerehabilitation for aphasia treatment

  This study tests whether a new online therapy for people with aphasia after a stroke works better than traditional in-person therapy.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT04682223

NIH-funded research (19)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding how vagus nerve stimulation helps stroke recovery to guide better treatments

  This NIH grant uses computer models to figure out how brief, task-timed vagus nerve stimulation affects the brain after stroke and helps movement recovery.

  NIH research University of Connecticut Storrs · Storrs-Mansfield, United States · NIH-11454679

• Calcium imaging guides deep brain stimulation to boost chronic stroke recovery in a rat model

  A research team is testing how customizing deep brain stimulation parameters in rats with stroke can improve long-term motor recovery, with the goal of guiding future patient treatments.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11377407

• Targeting synapse turnover to boost stroke recovery

  Aims to find ways to shape brain rewiring after stroke by guiding how synapses grow, with the goal of helping adults recover upper-limb function.

  NIH research University of Texas at Austin · Austin, United States · NIH-11368400

• Wearable EMG-FES System to Help Stroke Recovery and Find Biological Markers

  A wearable sleeve that uses your own muscle signals to help arm movement after stroke, while researchers look for biological clues that track recovery.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11336604

• Noradrenergic VNS to boost stroke rehab outcomes

  A patient-oriented look at a therapy that combines brief vagus nerve stimulation with physical rehab to help people recover arm movement after a stroke.

  NIH research University of Texas Dallas · Richardson, United States · NIH-11333269

• How rehab changes the brain after stroke

  This project will look at how rehabilitation training changes brain activity and connections after stroke to help people regain movement.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11262919

• Prism adaptation for right-brain stroke rehabilitation

  A personalized approach using prism adaptation to help people with spatial neglect after a right-hemisphere stroke improve everyday functioning.

  NIH research Northampton VA Medical Center · Leeds, United States · NIH-11248826

• Helping people recover after stroke by boosting brain cell energy

  The team is seeing if a drug that clears harmful fat debris and restores cell energy can limit brain damage and improve movement recovery after stroke.

  NIH research Southern Arizona VA Health Care System · Tucson, United States · NIH-11206889

• Improving Deep Brain Stimulation for Stroke Recovery

  This project aims to find better ways to use deep brain stimulation to help people recover movement after a stroke.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11168966

• Exploring how vagus nerve stimulation can improve recovery after a stroke

  This study is looking at how using a device that stimulates the vagus nerve during rehab exercises can help stroke survivors recover their movement skills better and faster.

  NIH research University of Texas Dallas · Richardson, United States · NIH-11097280

• How rehabilitation after a stroke affects brain recovery

  This study looks at how rehabilitation after a stroke helps the brain heal and regain movement, using monkeys to see how their brain activity changes when they start therapy soon after a stroke, with the goal of finding the best ways to help people recover their motor skills.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11075879

• Using prism adaptation treatment to help stroke survivors with spatial neglect

  This study is looking to help stroke survivors who have trouble noticing things on their left side by finding the best way to use a special therapy called prism adaptation therapy, so they can regain their independence and get the personalized support they need.

  NIH research Northampton VA Medical Center · Leeds, United States · NIH-11055410

• Improving recovery after stroke through enhanced mitochondrial function

  This study is looking at how a special compound called HPβCD might help stroke patients recover better by reducing inflammation and improving the health of their cells, which could lead to better movement and thinking skills during their rehabilitation.

  NIH research Southern Arizona VA Health Care System · Tucson, United States · NIH-10999058

• Using robots to enhance stroke rehabilitation in the community

  This study is looking at how using fun robotic games can help older stroke survivors recover by making therapy more engaging and social, so they can connect with others while improving their movement and communication skills.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10998763

• Understanding how brain stimulation can improve recovery after stroke

  This study is looking at how to make deep brain stimulation (DBS) work better for people recovering from strokes by testing it on rats, so we can find out why some people improve more than others and create personalized treatments for future patients.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-10979483

• Improving cognitive recovery after stroke using cooling and vibration therapies

  This study is looking at how using cool temperatures and gentle body vibrations together might help improve thinking and memory in people who have had a stroke, and it's being tested on older rats to see if it can lead to better treatments for stroke recovery in humans.

  NIH research Miami VA Health Care System · Miami, United States · NIH-10977033

• Investigating how sleep affects recovery after a stroke

  This study is looking at how sleep problems, like insomnia and restless legs syndrome, affect recovery for stroke patients, helping us understand how better sleep might improve their daily activities and mobility during rehabilitation.

  NIH research Upstate Medical University · Syracuse, United States · NIH-10849700

• Improving sleep for stroke patients during rehabilitation

  This study is looking at ways to help people recovering from strokes get better sleep, which is really important for healing, by reducing nighttime disruptions and checking for sleep problems, so they can feel stronger and recover more effectively.

  NIH research University of Chicago · Chicago, United States · NIH-10763378

• Improving arm movement recovery after stroke using targeted therapy

  This study is looking to help people who have had a stroke and struggle with moving their arms by using a special therapy that focuses on improving how their joints work together, making it easier for them to move their arms better.

  NIH research Northwestern University at Chicago · Chicago, United States · NIH-10694834

Related topics

Quick answers

How many Stroke Rehabilitation clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (4 trials), Taiwan (4 trials), France (2 trials), Pakistan (2 trials), Romania (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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