Digital rehabilitation system for stroke recovery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of a smartphone application that integrates virtual reality (VR) and augmented reality (AR) for at-home rehabilitation of stroke patients. It focuses on providing personalized motor and cognitive training for individuals in the late subacute and chronic phases post-stroke. Participants will be randomly assigned to either the VR/AR intervention or conventional therapy for six weeks, with assessments of motor function, cognitive function, and quality of life at multiple time points. The goal is to validate the PHRASE system's impact on recovery outcomes and its potential as a diagnostic tool.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients presenting an ischemic or intracerebral haemorrhagic stroke, ≥ 3 months post-stroke.
* Age \> 18 years old
* Moderate to mild proximal upper limb motor impairment Medical Research Council Scale (MRC \>2).
* ARAT: \<50, inclusive, to avoid ceiling effects while allowing room for improvement.
* Able to sit on a chair or a wheelchair to interact with the RGS system.
* Minimal experience with smartphone technology based on the clinician's opinion
* Willing to participate and agree to comply with the trial scheme and procedures
* Must sign an Informed Consent Form (ICF) indicating that they understand the purpose and the procedures of the study.

Exclusion Criteria:

* Presence of a condition or abnormality that, in the opinion of the investigator, would compromise the safety of the patient or the quality of the data.
* Severe cognitive capabilities that prevent the execution of the study, evaluated by the MoCA \< 19 or based on the clinician's opinion.
* Pre-stroke history of upper limb motor disability.
* Unable to use the RGS independently, according to the clinician's observations, and needing more support from a caregiver to use the RGS.

Where it's running

• RoNeuro Institute for Neurological Research and Diagnostics
  Cluj-Napoca, Romania Recruiting
• Hospital Universitari Joan XXIII de Tarragona
  Tarragona, Spain Recruiting

Study contacts

• Study coordinator: Santiago Brandi
• Email: contact@eodyne.com
• Phone: 34 931389642

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Home-based vs. in-clinic upper extremity rehabilitation after stroke

  This study tests whether a 20-hour home telerehabilitation program (tele-CPASS) works as well as the same in-clinic CPASS therapy for improving arm and hand function after stroke.

  Recruiting at 3 sites University of Texas, El Paso · El Paso, Texas and 2 other locations · NCT07661849

• Balance and fall risk after stroke: Sensorimotor training versus whole-body vibration

  A randomized study tests whether lower-limb sensorimotor training or whole-body vibration can improve balance and reduce fear of falling for people who have had a stroke.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT07642154

• kTMP-Enhanced Arm Rehabilitation in Chronic Stroke (KULMINATE) Pilot

  This pilot tests whether kTMP, a gentle brain stimulation method, can help improve arm and hand movement in adults with chronic stroke.

  Recruiting Magnetic Tides · San Francisco, California · NCT07631078

• Intermittent Theta Burst Stimulation (iTBS) to improve upper‑limb movement after chronic stroke

  This study will test if brief non‑invasive brain stimulation (iTBS) applied to the affected motor cortex plus regular physical therapy can improve arm and hand movement in adults who had a stroke more than six months earlier.

  Recruiting Danderyd Hospital · Stockholm · NCT07073248

• Intermittent Theta Burst Stimulation for lower limb recovery after chronic stroke

  This trial tests whether intermittent Theta Burst Stimulation (iTBS) of the cerebellum, combined with physical therapy, can improve leg movement and walking in people with chronic stroke.

  Recruiting Danderyd Hospital · Stockholm · NCT07073235

• Deep phenotyping to explore recovery in young adults after stroke

  This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.

  Recruiting The Florey Institute of Neuroscience and Mental Health · Heidelberg, Victoria and 1 other locations · NCT07019493

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.