Improving arm movement recovery after stroke using targeted therapy
Progressive Abduction Loading Therapy: A Phase IIb Stroke Rehabilitation Trial with Longitudinal Tracking
['FUNDING_R01'] · NORTHWESTERN UNIVERSITY AT CHICAGO · NIH-10694834
This study is looking to help people who have had a stroke and struggle with moving their arms by using a special therapy that focuses on improving how their joints work together, making it easier for them to move their arms better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHWESTERN UNIVERSITY AT CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-10694834 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing recovery of arm movement in individuals who have experienced a stroke, particularly those with severe impairments. It employs a therapy that targets independent joint control, aiming to reduce abnormal movement patterns through a data-driven intervention approach. The study builds on two decades of motor systems research and utilizes neuroimaging to understand how the brain's pathways can be optimized for better movement. Participants will engage in a structured rehabilitation program designed to improve their ability to move their arms against gravity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals in the chronic phase of stroke recovery who have severe upper extremity impairments.
Not a fit: Patients who have not experienced a stroke or those with mild impairments may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life for stroke survivors by enhancing their ability to perform daily activities independently.
How similar studies have performed: Previous research has shown promising results in improving motor control in stroke patients using similar targeted rehabilitation approaches.
Where this research is happening
CHICAGO, UNITED STATES
- NORTHWESTERN UNIVERSITY AT CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ELLIS, MICHAEL D. — NORTHWESTERN UNIVERSITY AT CHICAGO
- Study coordinator: ELLIS, MICHAEL D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.