Investigating how sleep affects recovery after a stroke
Official title: The SLEEPR study: SLEep Effects on Post-stroke Rehabilitation
Funded at Upstate Medical University · NIH-10849700 · Data updated 2026-11-12
This study is looking at how sleep problems, like insomnia and restless legs syndrome, affect recovery for stroke patients, helping us understand how better sleep might improve their daily activities and mobility during rehabilitation.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Upstate Medical University NIH-funded |
| Lab location | 1 site (Syracuse, United States) |
| Project start | September 16, 2020 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $598,850 |
| NIH project number | 5R01NR018979-05 |
| Project ID | NIH-10849700 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a stroke and are dealing with non-obstructive sleep disorders.
✕Less likely to help
Patients who have obstructive sleep apnea or other unrelated sleep disorders may not benefit from this research.
What this research studies
This research aims to explore the relationship between non-obstructive sleep apnea (non OSA) sleep disorders and recovery in stroke patients. It focuses on understanding how sleep quality impacts rehabilitation outcomes, including daily activities and mobility. By assessing the prevalence of sleep disorders like insomnia and restless legs syndrome in stroke survivors, the study seeks to identify how these conditions affect recovery. The research employs innovative methods to measure sleep patterns and their influence on rehabilitation progress.
Why it matters
Potential benefit: If successful, this research could lead to targeted sleep interventions that enhance recovery outcomes for stroke patients.
How similar studies have gone: Previous research has shown promising results in understanding the role of sleep in stroke recovery, but this specific focus on non OSA sleep disorders is relatively novel.
Where this research is happening
-
Upstate Medical University
Syracuse, United States Active
Researchers
- Principal investigator: Klingman, Karen J — Upstate Medical University
- Study coordinator: Klingman, Karen J
Related research
Other NIH-funded projects on the same topics.
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Understanding how vagus nerve stimulation helps stroke recovery to guide better treatments
This NIH grant uses computer models to figure out how brief, task-timed vagus nerve stimulation affects the brain after stroke and helps movement recovery.
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Calcium imaging guides deep brain stimulation to boost chronic stroke recovery in a rat model
A research team is testing how customizing deep brain stimulation parameters in rats with stroke can improve long-term motor recovery, with the goal of guiding future patient treatments.
-
Targeting synapse turnover to boost stroke recovery
Aims to find ways to shape brain rewiring after stroke by guiding how synapses grow, with the goal of helping adults recover upper-limb function.
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Wearable EMG-FES System to Help Stroke Recovery and Find Biological Markers
A wearable sleeve that uses your own muscle signals to help arm movement after stroke, while researchers look for biological clues that track recovery.
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Noradrenergic VNS to boost stroke rehab outcomes
A patient-oriented look at a therapy that combines brief vagus nerve stimulation with physical rehab to help people recover arm movement after a stroke.
-
How rehab changes the brain after stroke
This project will look at how rehabilitation training changes brain activity and connections after stroke to help people regain movement.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.