Clinical trial Recruiting at 4 sites Interventional Ages 20 to 80

Comparing two robotic therapy methods with exergaming for stroke rehabilitation

Official title: Proximal- Versus Distal-Prioritized Robotic Practice Plus Kinetic Exergaming in Stroke Rehabilitation

Run by Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation · NCT05492175 · Data updated 2026-11-12

This study is testing two different robotic therapy methods combined with fun video game exercises to see which one helps stroke patients recover better and improve their daily activities.

Quick facts

Study typeInterventional
Ages20 Years to 80 Years
SexAll
Enrollment72 (estimated)
SponsorTaipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Academic / other
Locations4 sites (Taichung and 3 other locations)
StatusRecruiting
StartedFebruary 17, 2022
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedFebruary 19, 2025
Trial IDNCT05492175 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 20 to 80 who have experienced their first stroke at least three months prior and meet specific functional criteria.

Probably not a fit

Patients with acute inflammation, pain, or other neurological conditions that may hinder participation will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research program investigates the effects of upper-limb robotic therapy combined with interactive exergaming in stroke rehabilitation. It aims to compare proximal versus distal priority robotic priming techniques to assess their impact on sensorimotor function, daily living activities, self-efficacy, quality of life, and motor control strategies in stroke patients. The study will also evaluate the retention effects of these approaches over three months and identify predictors of functional improvements after therapy.

Why it matters

Potential benefit: If successful, this approach could enhance recovery outcomes for stroke patients by improving motor function and quality of life.

How similar studies have gone: Other studies have shown promise in using robotic therapy and exergaming for rehabilitation, suggesting potential success for this innovative approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. a first ever-stroke≧3 months
2. age range between 20 to 80 years
3. baseline Fugl-Meyer assessment of upper extremity scale (FMA-UE) between 18 to 56
4. no excessive muscle spasticity of the affected extremities (Modified Ashworth Scale \< 3 at any joints)
5. able to follow examiners' commands and study instructions (Mini-Mental State Examination score≧22)
6. can maintain a step-standing position for at least 30 seconds
7. can walk for at least 10 meters with or without device
8. no participation in further experimental rehabilitation or drug studies during the duration of the project

Exclusion Criteria:

1. acute inflammation and pain
2. concomitant neurologic, neuromuscular or orthopedic conditions that may impede participation in this research.

Where it's running

  • Feng Yuan Hospital, Ministry of Health and Welfare
    Taichung, Taiwan
    Recruiting
  • National Taiwan University Hospital
    Taipei, Taiwan
    Recruiting
  • Taipei Municipal Wan Fang Hospital
    Taipei, Taiwan
    Recruiting
  • Taipei Tzu Chi Hospital
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.