Exploring how vagus nerve stimulation can improve recovery after a stroke

Noradrenergic mechanisms of vagus nerve stimulation mediated stroke rehabilitation

NIH-funded research University of Texas Dallas · NIH-11097280

This study is looking at how using a device that stimulates the vagus nerve during rehab exercises can help stroke survivors recover their movement skills better and faster.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Dallas NIH-funded
Lab location1 site (Richardson, United States)
Project IDNIH-11097280 on NIH RePORTER

What this research studies

This research investigates the use of vagus nerve stimulation (VNS) to enhance recovery of motor function in patients who have suffered a stroke. By applying brief bursts of VNS during rehabilitation exercises, the study aims to promote neuroplasticity in the brain's motor cortex, which is crucial for regaining movement abilities. The approach builds on previous successful trials and seeks to optimize the treatment to benefit more patients. Participants will engage in rehabilitative training while receiving VNS to potentially improve their upper limb function.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced a stroke and are facing challenges with upper limb mobility.

Not a fit: Patients who have not suffered a stroke or those with acute stroke conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved recovery outcomes for stroke patients, enhancing their ability to regain motor function.

How similar studies have performed: Previous studies have shown promising results with vagus nerve stimulation in enhancing recovery after stroke, indicating a potential for success in this research.

Where this research is happening

Richardson, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Attention deficit hyperactivity disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.