Improving sleep for stroke patients during rehabilitation
Official title: SIESTA (Sleep of Inpatients: Empower Staff to Act) for Acute Stroke Rehabilitation - Resubmission 01
Funded at University of Chicago · NIH-10763378 · Data updated 2026-11-12
This study is looking at ways to help people recovering from strokes get better sleep, which is really important for healing, by reducing nighttime disruptions and checking for sleep problems, so they can feel stronger and recover more effectively.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | January 22, 2020 |
| Project end | December 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $693,140 |
| NIH project number | 5R01HD097786-05 |
| Project ID | NIH-10763378 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are hospitalized for acute stroke rehabilitation.
✕Less likely to help
Patients who are not hospitalized for acute stroke or those with pre-existing severe sleep disorders may not benefit from this research.
What this research studies
This research focuses on enhancing sleep quality for patients recovering from acute strokes, which is crucial for their rehabilitation. It addresses two main challenges: unnecessary nighttime interruptions from medical care and the risk of undiagnosed sleep disorders. A team of experts will implement and evaluate a tailored intervention, SIESTA-Rehab, designed to promote restorative sleep during the critical rehabilitation phase. By improving sleep, the study aims to support better recovery outcomes and physical function.
Why it matters
Potential benefit: If successful, this research could significantly improve recovery and rehabilitation outcomes for stroke patients by enhancing their sleep quality.
How similar studies have gone: Previous research has shown that improving sleep quality can enhance recovery outcomes in stroke patients, indicating a promising approach.
Where this research is happening
-
University of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Arora, Vineet — University of Chicago
- Study coordinator: Arora, Vineet
Related research
Other NIH-funded projects on the same topics.
-
Understanding how vagus nerve stimulation helps stroke recovery to guide better treatments
This NIH grant uses computer models to figure out how brief, task-timed vagus nerve stimulation affects the brain after stroke and helps movement recovery.
-
In-bed wearable rehab robot to help stroke survivors recover movement
A wearable robotic device will be developed to help adults who recently had an acute stroke regain movement while still in the hospital.
-
When people are most at risk of another stroke after a minor stroke or TIA
Researchers are combining past trial data to find the timing of highest risk for a second stroke after a minor stroke or TIA so treatments can be better timed.
-
Improving Participation after Stroke: Self-Management Rehab for Sub-Acute Stroke
A doctor- and patient-friendly program delivered virtually helps people who recently had a stroke feel more confident, stay active at home, and improve quality of life.
-
Targeting a brain inflammation regulator to protect cells after a stroke
Aims to test a new approach that tampers with a key brain cell regulator to reduce inflammation and protect brain tissue after a stroke, potentially lowering disability.
-
Predicting brain tissue outcome after acute stroke using AI
A researchers at Stanford are testing an AI system that uses brain scans and clinical data to predict which parts of the brain will recover after an acute stroke and how treatment might help.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.