Music therapy for stroke rehabilitation in patients with non-fluent aphasia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop and test an Indian adaptation of Melodic Intonation Therapy (MIT) for patients suffering from post-stroke non-fluent aphasia. The research will be conducted in two stages: first, formulating a therapy module with input from speech-language therapists and music experts, and second, assessing the feasibility and effectiveness of this therapy compared to standard speech rehabilitation. A total of 70 patients will be recruited, with randomization into intervention and control groups to evaluate speech recovery over 12 weeks.

Why it matters

Who can join: the full rules

Inclusion Criteria:

All of the following

1. Age ≥18 years of age
2. Stroke with non-fluent aphasia, within one year of ictus
3. Imaging evidence suggestive of ischemic or hemorrhagic stroke of dominant hemisphere
4. Patient is alert and able to follow simple commands (should not have global aphasia)
5. Motivated caregiver
6. Informed and signed consent

Exclusion Criteria:

Any of the following:

1. Patients with a history of a previous stroke other than the index event, which can explain the aphasia.
2. Any clinical condition (e.g., short life expectancy, coexisting disease) or other characteristics that preclude appropriate follow-up in the study (e.g., distant residence, no family support)
3. Patients participating in any therapeutic intervention clinical trials evaluating poststroke recovery
4. Use of psychotropic drugs that interfere with patient evaluation

Where it's running

• Institute of Human Behavior and Allied Sciences
  Delhi, National Capital Territory of Delhi, India Recruiting
• All India Institute of Medical Sciences, New Delhi
  New Delhi, National Capital Territory of Delhi, India Recruiting
• Safdarjung Hospital
  New Delhi, National Capital Territory of Delhi, India Recruiting

Study contacts

• Study coordinator: Deepti Vibha
• Email: deeptivibha@aiims.edu
• Phone: +91-9868398263

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.