Clinical trial Recruiting at 5 sites Interventional Ages 30 to 80

Combining mirror therapy and augmented reality for stroke rehabilitation

Official title: Outcomes of Mirror Therapy Preceding Augmented Reality in Stroke Rehabilitation

Run by National Taiwan University Hospital · NCT05993091 · Data updated 2026-11-12

This study tests whether using a combination of mirror therapy and augmented reality can help people who have had a stroke recover better and faster.

Quick facts

Study typeInterventional
Ages30 Years to 80 Years
SexAll
Enrollment75 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Locations5 sites (New Taipei City and 4 other locations)
StatusRecruiting
StartedMay 5, 2023
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedFebruary 5, 2026
Trial IDNCT05993091 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 30 to 80 who have experienced a first-ever unilateral stroke between 3 months and 3 years prior.

Probably not a fit

Patients with severe spasticity, acute inflammation, or other serious medical conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research aims to explore innovative treatment strategies for stroke rehabilitation by combining mirror therapy (MT) with augmented reality (AR). The study focuses on patients who have experienced a first-ever unilateral stroke and are within 3 months to 3 years post-event. By utilizing AR, the intervention provides an intensive and context-rich training program that enhances motivation and participation through real-time feedback. The goal is to create an enriched neuroplastic environment that facilitates motor and functional recovery in stroke patients.

Why it matters

Potential benefit: If successful, this approach could significantly improve rehabilitation outcomes for stroke patients, enhancing their recovery and quality of life.

How similar studies have gone: While the combination of MT and AR is a novel approach, previous studies have shown promise in using these individual therapies for stroke rehabilitation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. a first-ever unilateral stroke ≥3 months and ≤3 years
2. age between 30 and 80 years (Kwakkel et al., 1999)
3. baseline Fugl-Meyer Assessment Upper Extremity (FMA-UE) score \>10 (Fugl-Meyer et al., 1975)
4. no severe spasticity in any joints of the affected arm (modified Ashworth scale \<3) (Charalambous, 2014)
5. ability to follow the instructions of the evaluator and therapists
6. the ability to maintain a step-standing position for at least 30 seconds (Lloréns et al., 2015)
7. ability to walk a minimum of 10 meters, with or without a device (Park et al., 2017)
8. no severe vision impairments or other major neurologic diseases
9. no participation in other studies during the study period
10. willingness to provide informed written consent.

Exclusion Criteria:

1. acute inflammation
2. serious medical problems or poor physical conditions that might be detrimental to study participation.

Where it's running

  • Taipei Hospital, Ministry of Health and Welfare
    New Taipei City, Taiwan
    Recruiting
  • Taipei Tzu Chi Hospital, Buddhist Tzu Chi Foundation
    New Taipei City, Taiwan
    Recruiting
  • Fongyuan Hospital, Ministry of Health and Welfare
    Taichung, Taiwan
    Recruiting
  • National Taiwan University Hospital
    Taipei, Taiwan
    Recruiting
  • Wan Fang Hospital, Taipei Medical University
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.