Combining mirror therapy and augmented reality for stroke rehabilitation
Official title: Outcomes of Mirror Therapy Preceding Augmented Reality in Stroke Rehabilitation
Run by National Taiwan University Hospital · NCT05993091 · Data updated 2026-11-12
This study tests whether using a combination of mirror therapy and augmented reality can help people who have had a stroke recover better and faster.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 80 Years |
| Sex | All |
| Enrollment | 75 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 5 sites (New Taipei City and 4 other locations) |
| Status | Recruiting |
| Started | May 5, 2023 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | February 5, 2026 |
| Trial ID | NCT05993091 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 30 to 80 who have experienced a first-ever unilateral stroke between 3 months and 3 years prior.
✕Probably not a fit
Patients with severe spasticity, acute inflammation, or other serious medical conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research aims to explore innovative treatment strategies for stroke rehabilitation by combining mirror therapy (MT) with augmented reality (AR). The study focuses on patients who have experienced a first-ever unilateral stroke and are within 3 months to 3 years post-event. By utilizing AR, the intervention provides an intensive and context-rich training program that enhances motivation and participation through real-time feedback. The goal is to create an enriched neuroplastic environment that facilitates motor and functional recovery in stroke patients.
Why it matters
Potential benefit: If successful, this approach could significantly improve rehabilitation outcomes for stroke patients, enhancing their recovery and quality of life.
How similar studies have gone: While the combination of MT and AR is a novel approach, previous studies have shown promise in using these individual therapies for stroke rehabilitation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. a first-ever unilateral stroke ≥3 months and ≤3 years 2. age between 30 and 80 years (Kwakkel et al., 1999) 3. baseline Fugl-Meyer Assessment Upper Extremity (FMA-UE) score \>10 (Fugl-Meyer et al., 1975) 4. no severe spasticity in any joints of the affected arm (modified Ashworth scale \<3) (Charalambous, 2014) 5. ability to follow the instructions of the evaluator and therapists 6. the ability to maintain a step-standing position for at least 30 seconds (Lloréns et al., 2015) 7. ability to walk a minimum of 10 meters, with or without a device (Park et al., 2017) 8. no severe vision impairments or other major neurologic diseases 9. no participation in other studies during the study period 10. willingness to provide informed written consent. Exclusion Criteria: 1. acute inflammation 2. serious medical problems or poor physical conditions that might be detrimental to study participation.
Where it's running
-
Taipei Hospital, Ministry of Health and Welfare
New Taipei City, Taiwan Recruiting -
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Foundation
New Taipei City, Taiwan Recruiting -
Fongyuan Hospital, Ministry of Health and Welfare
Taichung, Taiwan Recruiting -
National Taiwan University Hospital
Taipei, Taiwan Recruiting -
Wan Fang Hospital, Taipei Medical University
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Keh-chung Lin, ScD — National Taiwan University Hospital
- Study coordinator: Keh-chung Lin, ScD
- Email: kehchunglin@ntu.edu.tw
- Phone: +886-3366-8180
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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NDT vs. Mirror Therapy for lower limb recovery after sub-acute stroke
This trial tests whether neurodevelopmental technique (NDT) or mirror therapy (MT) helps improve leg coordination and walking in people 45–65 with sub-acute stroke.
-
Home-based vs. in-clinic upper extremity rehabilitation after stroke
This study tests whether a 20-hour home telerehabilitation program (tele-CPASS) works as well as the same in-clinic CPASS therapy for improving arm and hand function after stroke.
-
Balance and fall risk after stroke: Sensorimotor training versus whole-body vibration
A randomized study tests whether lower-limb sensorimotor training or whole-body vibration can improve balance and reduce fear of falling for people who have had a stroke.
-
Cerebello-spinal direct current stimulation to improve walking in chronic stroke
Test whether cerebello-spinal direct current stimulation combined with daily treadmill training improves walking and mobility in people who had a stroke at least six months ago.
-
Brain pathways that support arm recovery after stroke
This trial will try 30 hours (over 6 weeks) of targeted Arm Basis Training versus usual care to see if it improves proximal arm motor control in people 3–6 months after a first ischemic or hemorrhagic stroke with moderate to severe arm impairment.
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Curved walking paired with a second task to aid stroke recovery
This will test whether practicing curved walking while doing a simple mental task helps thinking and walking for people recovering from a first-time stroke.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.