Condition

Spondyloarthritis clinical trials and research

• 10Clinical trials
• 6NIH research projects
• 2Countries

Newest Spondyloarthritis clinical trials

All recruiting trials (10)

• Impact of ultra-processed foods on rheumatic diseases

  This study looks at how eating ultra-processed foods might affect people with chronic rheumatic diseases like rheumatoid arthritis and osteoarthritis to see if it makes their symptoms worse.

  Recruiting Hospices Civils de Lyon · Lyon · NCT06776965

• Digital exercise program for patients with spondyloarthritis

  This study is testing a digital exercise program to see if it helps people with axial spondyloarthritis feel better compared to regular care.

  Recruiting Diakonhjemmet Hospital · Oslo · NCT06462937

• Fecal microbiota transplantation for treating axial spondyloarthritis

  This study is testing if a treatment using gut bacteria from healthy donors can help people with axial spondyloarthritis who aren't feeling better with their current medications.

  Recruiting Phase 2 University Hospital of North Norway · Tromsø · NCT06451588

• Exploring the role of IL-23 in spondyloarthritis

  This study is trying to see how a protein called IL-23 affects immune cells in people with spondyloarthritis to better understand the disease and its different types.

  Recruiting at 2 sites Institut Pasteur · Créteil and 3 other locations · NCT05290363

• Biobank for patients with inflammatory chronic diseases and osteoporosis

  This study is creating a biobank to collect samples from patients with chronic inflammatory diseases and osteoporosis to see if they can find markers that help doctors choose better treatments.

  Recruiting University Hospital, Toulouse · Toulouse · NCT05039216

• Gut bacteria test to predict response to biologic treatment in spondyloarthritis

  This project will test whether gut bacteria in stool samples can predict if anti-TNF or anti-IL-17 biologic treatment will work for adults with spondyloarthritis.

  Recruiting Hôpital Européen Marseille · Marseille · NCT04899154

• Exploring the link between gut bacteria and spondyloarthritis

  This study is testing if a specific gut bacteria called Ruminococcus gnavus is linked to spondyloarthritis by comparing patients with the condition to healthy people.

  Recruiting Assistance Publique - Hôpitaux de Paris · Boulogne-Billancourt · NCT04853212

• Characterizing gut bacteria in people with spondyloarthritis or rheumatoid arthritis

  This project will test whether the mix of gut bacteria differs between adults with spondyloarthritis or rheumatoid arthritis and healthy volunteers by analyzing stool and blood samples.

  Recruiting Assistance Publique - Hôpitaux de Paris · Boulogne-Billancourt · NCT04292067

• Understanding chronic inflammatory systemic diseases and their treatments

  This study looks at patients with chronic inflammatory diseases to see how these conditions are related and how they can be treated better.

  Recruiting Centre Hospitalier Universitaire de Besancon · Besançon · NCT04191395

• Identifying gut bacteria linked to spondyloarthritis in Crohn's disease patients

  This study is trying to find out if certain gut bacteria are linked to spondyloarthritis in people who have Crohn's disease by comparing them to healthy individuals and those with just one of the conditions.

  Recruiting at 2 sites Central Hospital, Nancy, France · Nancy, Lorraine and 1 other locations · NCT03983473

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding early triggers of axial spondyloarthritis in people at risk

  This grant aims to understand the early immune changes that lead to axial spondyloarthritis in people who carry a genetic risk, with new peptide tools to distinguish harmful from protective T cells.

  NIH research Washington University · Saint Louis, United States · NIH-11448793

• Pathogenic T cells in axial spondyloarthritis and eye inflammation

  Researchers are studying eye-specific and shared immune mechanisms in axial spondyloarthritis to understand how T cells contribute to eye inflammation and related joint disease, with findings that could guide future treatments.

  NIH research Washington University · Saint Louis, United States · NIH-11370581

• Identifying harmful immune cells in axial spondyloarthritis

  This study is looking at how certain immune cells affect eye inflammation in people with axial spondyloarthritis, which could help us understand how this condition impacts both the eyes and joints.

  NIH research Washington University · Saint Louis, United States · NIH-11292090

• Identifying predictors of flare in children with spondyloarthritis

  This study is looking at how specific blood tests and MRI results can help predict flare-ups in kids with spondyloarthritis, so families can make better choices about their child's treatment and safely reduce the use of strong medications that might have side effects.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11051161

• Improving care for children with juvenile spondyloarthritis

  This study is all about helping doctors who specialize in children's joint diseases, like juvenile spondyloarthritis, by training them better so they can do research that leads to improved care for kids with these conditions.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-10898717

• Identifying harmful T cells in a type of arthritis that affects the spine and eyes

  This study is looking at how certain immune cells, called CD8 T cells, behave in people with axial spondyloarthritis, especially when it causes eye inflammation, to help us understand the condition better and find new ways to treat it.

  NIH research Washington University · Saint Louis, United States · NIH-10878955

Related topics

Quick answers

How many Spondyloarthritis clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in France (8 trials), Norway (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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