Improving care for children with juvenile spondyloarthritis
Official title: Mentoring and Patient Oriented Research in Juvenile Spondyloarthritis
Funded at Children's Hosp of Philadelphia · NIH-10898717 · Data updated 2026-11-12
This study is all about helping doctors who specialize in children's joint diseases, like juvenile spondyloarthritis, by training them better so they can do research that leads to improved care for kids with these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 1, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $132,715 |
| NIH project number | 5K24AR078950-03 |
| Project ID | NIH-10898717 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children diagnosed with juvenile spondyloarthritis or those showing symptoms of the condition.
✕Less likely to help
Patients who are adults or do not have juvenile spondyloarthritis may not receive any benefit from this research.
What this research studies
This research focuses on enhancing the training and mentoring of physician scientists in pediatric rheumatology to improve patient-oriented research. It aims to address challenges in diagnosing and treating juvenile spondyloarthritis by developing better imaging criteria and leveraging existing studies. The project will train junior faculty and peers to effectively manage mentoring relationships and navigate the research environment, ultimately aiming to improve clinical care for affected children.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic criteria and treatment options for children suffering from juvenile spondyloarthritis.
How similar studies have gone: Previous research has shown promise in improving diagnostic imaging techniques for juvenile arthritis, indicating that this approach could yield beneficial results.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Weiss, Pamela Fitch — Children's Hosp of Philadelphia
- Study coordinator: Weiss, Pamela Fitch
Related research
Other NIH-funded projects on the same topics.
-
Understanding early triggers of axial spondyloarthritis in people at risk
This grant aims to understand the early immune changes that lead to axial spondyloarthritis in people who carry a genetic risk, with new peptide tools to distinguish harmful from protective T cells.
-
Pathogenic T cells in axial spondyloarthritis and eye inflammation
Researchers are studying eye-specific and shared immune mechanisms in axial spondyloarthritis to understand how T cells contribute to eye inflammation and related joint disease, with findings that could guide future treatments.
-
Identifying harmful immune cells in axial spondyloarthritis
This study is looking at how certain immune cells affect eye inflammation in people with axial spondyloarthritis, which could help us understand how this condition impacts both the eyes and joints.
-
Identifying predictors of flare in children with spondyloarthritis
This study is looking at how specific blood tests and MRI results can help predict flare-ups in kids with spondyloarthritis, so families can make better choices about their child's treatment and safely reduce the use of strong medications that might have side effects.
-
Identifying harmful T cells in a type of arthritis that affects the spine and eyes
This study is looking at how certain immune cells, called CD8 T cells, behave in people with axial spondyloarthritis, especially when it causes eye inflammation, to help us understand the condition better and find new ways to treat it.
-
Impact of ultra-processed foods on rheumatic diseases
This study looks at how eating ultra-processed foods might affect people with chronic rheumatic diseases like rheumatoid arthritis and osteoarthritis to see if it makes their symptoms worse.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.