Condition

Self-management clinical trials and research

• 10Clinical trials
• 146NIH research projects
• 9Countries

Newest Self-management clinical trials

All recruiting trials (10)

• Think-Find-Solve activities for insulin self-management in children with type 1 diabetes

  A behavior-change activity book is tested with children aged 8–12 with type 1 diabetes and their parents to see if it improves daily insulin self-management.

  Recruiting Marmara University · Istanbul · NCT07670572

• Asthma self-management education for adults in primary care

  This study tests whether a new asthma self-management program helps adults in Ireland manage their symptoms better.

  Recruiting Royal College of Surgeons, Ireland · Dublin, D · NCT07609134

• Endometriosis self-management in Europe

  This study follows people with endometriosis in Europe to see how daily self-management, support from others, and care systems influence their sense of empowerment or abandonment.

  Recruiting Wageningen University and Research · Wageningen · NCT07591441

• Dyadic self-management with caregivers for older adults with diabetes and cognitive concerns

  This study tests whether adding caregiver support to a Chronic Disease Self-Management Program helps older adults with diabetes and mild cognitive impairment see better diabetes control and cognitive function.

  Recruiting The Hong Kong Polytechnic University · Hong Kong · NCT07496359

• Heart Failure Carer Support Programme: Testing How to Deliver Help for Carers in the UK

  This trial tests a support program for informal carers of heart failure patients to see if it improves wellbeing for both carers and the patients they care for.

  Recruiting Queen's University, Belfast · Belfast and 4 other locations · NCT07373041

• Using language nudges and a medication-preference app to boost shared decision-making and self-care in type 2 diabetes

  This trial will test whether training doctors to use short language 'nudges' plus a mobile app for recording medication preferences helps adults with type 2 diabetes make treatment choices and stick to their medicines.

  Recruiting Xiamen University · Xiamen, Fujian · NCT07129915

• Digital health app to help manage Chronic Obstructive Pulmonary Disease

  This study is testing a new mobile app that helps people with COPD manage their symptoms better by providing personalized breathing exercises and support from physiotherapists.

  Recruiting Western Norway University of Applied Sciences · Bergen, Norway · NCT06850961

• Motivational interviewing to improve diabetes self-management and reduce cyberchondria

  This study is testing if motivational interviewing can help people with Type 2 diabetes better manage their condition and reduce their anxiety about health information found online.

  Recruiting Ataturk University · Van, Van · NCT06826703

• Assessing self-efficacy and well-being in patients with fibrotic interstitial lung disease

  This study is trying to see how patients with fibrotic interstitial lung disease feel about their quality of life and confidence in managing their health before and after rehabilitation or outpatient care.

  Recruiting at 2 sites Berner Reha Zentrum AG · Bern, Canton of Bern and 1 other locations · NCT06027333

• Improving medication adherence and blood pressure control in older African Americans

  This study is testing a new technology-based program to help older African Americans better manage their high blood pressure and improve their overall health.

  Recruiting Case Western Reserve University · Cleveland, Ohio · NCT05293756

NIH-funded research (newest 40 of 146)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Michigan Diabetes Project: A Peer-Led Self-Management Program for Adults with Type 2 Diabetes

  A peer-led self-management program for adults with type 2 diabetes is being tested to see if it improves blood sugar control and daily diabetes care.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11594416

• Economic evaluation of MEW Network epilepsy self-management programs for broad adoption

  This project tests how cost-effective two epilepsy self-management programs (UPLIFT and PACES) are when used in real-world healthcare and community settings, to help people with epilepsy live better.

  NIH research New York University School of Medicine · New York, United States · NIH-11503930

• Economic analysis of the MEW self-management program for epilepsy (MINDSET) in real-world settings

  This grant studies how a proven epilepsy self-management program can be implemented in communities and clinics, and how its costs and benefits stack up.

  NIH research University of Arizona · Tucson, United States · NIH-11503929

• EDGE: A personalized, digital diabetes support program with real-time glucose feedback

  A digital program for adults with type 2 diabetes uses real-time glucose data, coaching, and engaging features to help them manage their condition better.

  NIH research Scripps Health · San Diego, United States · NIH-11451249

• Self-management Apps with AI to Help Emerging Adults Reduce Substance Use and Costs

  A new AI-powered self-management program for 18- to 25-year-olds with substance use issues aims to reduce use, overdoses, and costs by delivering scalable, smartphone-based support.

  NIH research Chestnut Health Systems, INC. · Bloomington, United States · NIH-11448904

• AI-powered, person-centered chatbot to help manage menstrual pain

  A patient-friendly AI chatbot called PeriodPal will provide evidence-based, personalized tips to help manage dysmenorrhea and reduce days missed from work or school.

  NIH research University of Arizona · Tucson, United States · NIH-11436001

• OASIS: a personalized cancer symptom app to help you manage treatment burden

  A mobile app helps adults undergoing cancer treatment track symptoms, get tailored tips, and connect with support to feel better and stay on track with their care.

  NIH research University of Iowa · Iowa City, United States · NIH-11426033

• Adapted DSMES Digital Health for Mexican-origin Hispanics with Type 2 Diabetes

  A digital health program adapted from an in-person diabetes education approach is designed to help Mexican-origin adults with type 2 diabetes improve self-management and access to care.

  NIH research University of Texas El Paso · El Paso, United States · NIH-11419919

• Integrated self-management support for asthma and depression in older adults

  A program that combines asthma self-management with depression-focused therapy to help older adults control asthma and feel better.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11417988

• Lifelong self-management with an AI mentor for chronic conditions

  A personalized AI assistant helps adults with chronic conditions, like multiple sclerosis, manage daily health needs over their lifetime.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11417328

• Thinking skills and self-care after a liver transplant

  This project follows people who received liver transplants to learn how changes in thinking and memory affect managing medicines, clinic visits, and overall health.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11398886

• Internet-delivered pain self-management for pancreatitis

  A digital cognitive-behavioral therapy program helps people with recurrent acute or chronic pancreatitis reduce pain and how much it interferes with daily life.

  NIH research Seattle Children's Hospital · Seattle, United States · NIH-11398838

• Phone-based support to help young adults in Zambia manage HIV and reduce substance use

  This project will try a mobile program with brief counseling sessions plus motivational text messages to help 18–24-year-olds in Zambia stay on HIV treatment and cut back on alcohol or drugs.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11393465

• Audio recordings of clinic visits to support self-management for older adults with diabetes

  A three-site study will test whether giving older adults with diabetes an audio recording of their clinic visit, in addition to the usual after-visit summary, helps them remember and manage their health.

  NIH research Dartmouth College · Hanover, United States · NIH-11390433

• Personalized ear acupressure to manage chronic musculoskeletal pain in rural adults

  This project teaches rural adults with long-standing musculoskeletal pain to use a personalized ear-acupressure program with a smartphone app so they can manage pain themselves.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11381463

• Improving Participation after Stroke: Self-Management Rehab for Sub-Acute Stroke

  A doctor- and patient-friendly program delivered virtually helps people who recently had a stroke feel more confident, stay active at home, and improve quality of life.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-11381081

• Telerehabilitation to help older Veterans manage multiple health problems

  This compares a home-based telerehabilitation program plus coaching to usual care for older Veterans with multiple medical conditions to help them stay active and manage daily function.

  NIH research VA Eastern Colorado Health Care System · Aurora, UNITED STATES · NIH-11380361

• A family-friendly approach to help teens with SCD manage their health

  A teen-focused program uses group therapy plus a mobile app to help adolescents with sickle cell disease manage their care and reduce painful episodes.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11377309

• Heuristic tool helps adolescents and young adults with cancer manage symptoms

  A randomized trial tests a computer-based symptom tool to help teens and young adults with cancer manage their symptoms with their care team.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11376165

• Helping people with heart failure and mild thinking problems manage their care through mindfulness and body-awareness

  This project teaches mindfulness and attention skills to help people with heart failure and mild thinking problems notice symptoms and follow medicines and lifestyle advice more reliably.

  NIH research Miriam Hospital · Providence, United States · NIH-11372024

• Perioperative pain self-management to prevent long-term pain and opioid use

  This project tests whether a short cognitive-behavioral perioperative pain self-management program helps surgical patients avoid chronic post-surgical pain and prolonged opioid use.

  NIH research Iowa City VA Medical Center · Iowa City, United States · NIH-11370957

• Digital self-management and peer mentoring to help childhood cancer survivors transition to adult care

  A digital, mentor-supported program helps young survivors manage their health as they move from pediatric to adult follow-up care.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11370853

• Self-management Intervention to Reduce Epilepsy Burden in Ugandans with Epilepsy

  A program helps people with epilepsy in Uganda manage their condition daily to improve quality of life and reduce stigma.

  NIH research Makerere University College of Health Sciences · Kampala, Uganda · NIH-11345942

• Strengths-based program to boost resilience and self-management in youths with Type 1 diabetes

  A youth-focused program uses strengths-based strategies to help children and teens with Type 1 diabetes manage their care better and stay on track during early adolescence.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11345111

• Optimizing diabetes self-management programs for people with high burden of disease

  Aimed at adults with poorly controlled type 2 diabetes, this project tests ways to make diabetes education more engaging and effective in real-world communities.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11342281

• AI-enhanced text messaging to help adults manage mental health symptoms

  A 4-year project from Northwestern uses automated text messages, boosted by AI, to help adults manage mood and anxiety and stay engaged with self-care strategies.

  NIH research Northwestern University · Chicago, United States · NIH-11330099

• Adaptive symptom self-management to ease distress for cancer survivors on immune checkpoint inhibitors

  A study tests a phone-based symptom-monitoring program, with tailored support, to help cancer survivors on immune checkpoint inhibitors feel less distressed and manage side effects.

  NIH research University of Arizona · Tucson, United States · NIH-11326259

• SmartStart: a digital diabetes self-management support for people with new type 2 diabetes who have low income

  A digital program helps adults with new type 2 diabetes who have low income manage their health better right after diagnosis.

  NIH research Arizona State University-Tempe Campus · Scottsdale, United States · NIH-11324032

• Cancer Care Companion: an EHR tool to help parents of children with cancer

  This project will build and pilot an Epic MyChart-based Care Companion to help parents of young children with cancer track symptoms, access education, and message clinicians.

  NIH research Washington University · Saint Louis, United States · NIH-11321108

• Mobile EEG headband and app to manage chronic low back pain

  This trial will see whether a portable EEG headband and smartphone app help adults with chronic low back pain reduce their pain when used at home.

  NIH research Duke University · Durham, United States · NIH-11310005

• How COVID-19 affects managing long-term health conditions

  Researchers are following middle-aged and older adults with one or more chronic conditions to learn how the COVID-19 pandemic changed their ability to manage health and get care.

  NIH research Northwestern University · Chicago, United States · NIH-11306581

• Improving COPD self-care programs

  This project tries different parts of a COPD self-care program—education, physical activity, and inhaler training—to see which combinations help adults with COPD who had a flare-up in the past year.

  NIH research Rush University Medical Center · Chicago, United States · NIH-11301806

• Family-based self-management support for youth with spina bifida

  A patient-facing program designed to help children with spina bifida and their caregivers manage daily health tasks at home.

  NIH research Loyola University Chicago · Maywood, United States · NIH-11298723

• Comprehensive home-based coaching to help COPD patients manage their care

  A doctor-managed program helps adults with COPD manage daily treatments, recognize early signs of flare-ups, and access home-based rehab with support from community health workers.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11292426

• Self-care support for teens and young adults with sickle cell

  A smartphone-based self-care program helps adolescents and young adults with sickle cell disease build everyday management skills as they move to adult care.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11285152

• Helping young people with Type 1 diabetes build resilience and manage their care

  This program uses mobile apps, brief family goal meetings, and positive clinic support to help early adolescents with Type 1 diabetes manage blood sugar and feel better about daily care.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11239042

• Using mobile health technology to help advanced cancer patients manage chronic pain

  This study is testing a new smartphone app that helps people with advanced cancer manage their pain better by using techniques from therapy, making it easier for them to get support without needing to go to appointments.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11236544

• Bilingual online diabetes self-care program for Mexican-origin Hispanic adults

  This project will turn a community-led bilingual diabetes education program into an online course to help Mexican-origin Hispanic adults with type 2 diabetes manage their health more easily.

  NIH research University of Texas El Paso · El Paso, United States · NIH-11234769

• Path to Better Sleep: online insomnia program with virtual coaching for Veterans

  This program offers Veterans with insomnia an online CBTi course called Path to Better Sleep plus virtual coaching to help them complete the program and sleep better.

  NIH research VA Connecticut Healthcare System · West Haven, United States · NIH-11231661

• A digital program to help low-income individuals manage their newly diagnosed type 2 diabetes

  This study is testing a new phone-based program to help people with low incomes who have just been diagnosed with type 2 diabetes learn how to manage their condition better and get the support they need.

  NIH research Arizona State University-Tempe Campus · Tempe, United States · NIH-11228855

Related topics

Quick answers

How many Self-management clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in Turkey (Türkiye) (2 trials), Netherlands (1 trial), United States (1 trial), Ireland (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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