NIH-funded research R01 grant

Helping people with heart failure and mild thinking problems manage their care through mindfulness and body-awareness

Official title: Targeting cognitive function and interoceptive awareness to improve self-management in patients with co-morbid heart failure and cognitive impairment.

Funded at Miriam Hospital · NIH-11372024 · Data updated 2026-11-12

This project teaches mindfulness and attention skills to help people with heart failure and mild thinking problems notice symptoms and follow medicines and lifestyle advice more reliably.

More Heart Failure research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMiriam Hospital
NIH-funded
Lab location1 site (Providence, United States)
Project startMay 5, 2022
Project endApril 30, 2027
Funding year2026
Award (this year)$644,639
NIH project number5R01AG076438-05
Project IDNIH-11372024 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults with diagnosed heart failure who also have mild cognitive impairment, can provide informed consent, and can attend the Providence study site visits.

Less likely to help

People without heart failure, without cognitive impairment, with severe dementia, or who cannot participate in required visits are unlikely to benefit from this intervention.

What this research studies

You would learn mindfulness practices and exercises to improve attention and awareness of internal bodily signals that can signal worsening heart failure. Sessions combine attention training, relaxation techniques that support vagal (parasympathetic) control, and practical strategies to support daily self-care like taking medicines and monitoring symptoms. The team will track thinking skills, symptom awareness, self-care behaviors, and clinical outcomes such as hospital readmissions, and may collect biological markers related to heart and brain function. The program is delivered through Miriam Hospital with regular sessions and follow-up over several months.

Why it matters

Potential benefit: If successful, this could help people with heart failure and mild cognitive problems notice worsening symptoms earlier, stick to treatments better, and reduce hospital readmissions.

How similar studies have gone: Small prior studies suggest mindfulness can improve attention and interoceptive awareness and may help cognitive function, but applying these methods specifically to people with both heart failure and mild cognitive impairment is relatively new.

Where this research is happening

  • Miriam Hospital
    Providence, United States
    Active

Researchers

  • Principal investigator: Salmoirago-Blotcher, Elena — Miriam Hospital
  • Study coordinator: Salmoirago-Blotcher, Elena

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.