NIH-funded research R01 grant

Adaptive symptom self-management to ease distress for cancer survivors on immune checkpoint inhibitors

Official title: Adaptive Symptom Self-Management to Reduce Psychological Distress and Improve Symptom Management for Survivors on Immune Checkpoint Inhibitors

Funded at University of Arizona · NIH-11326259 · Data updated 2026-11-12

A study tests a phone-based symptom-monitoring program, with tailored support, to help cancer survivors on immune checkpoint inhibitors feel less distressed and manage side effects.

More Self-management research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Arizona
NIH-funded
Lab location1 site (Tucson, United States)
Project startMay 1, 2022
Project endApril 30, 2027
Funding year2026
Award (this year)$634,069
NIH project number5R01CA263714-05
Project IDNIH-11326259 on NIH RePORTER

Who could benefit from this research

Could help

Adults with cancer who are starting immune checkpoint inhibitors and experiencing elevated psychological distress within 12 weeks of treatment.

Less likely to help

Patients with low distress or those not using immune checkpoint inhibitors may not directly benefit from this specific intervention.

What this research studies

If you are a cancer survivor starting immune checkpoint inhibitors, you may be invited to join a sequential randomization study that uses weekly automated phone check-ins about symptoms. Depending on how you respond, you could receive additional support designed to boost your confidence in managing symptoms and communicating with your healthcare team. The program sends symptom summaries to your doctors and provides you with easy-to-use self-management tips and a printed handbook. The goal is to reduce psychological distress and keep treatment on track by catching problems early. The study is being led by researchers at the University of Arizona and will enroll a diverse group of participants.

Why it matters

Potential benefit: Participants could experience better symptom control and lower distress, potentially reducing treatment interruptions.

How similar studies have gone: Previous similar symptom-monitoring approaches have shown improvements in symptom management and engagement with care.

Where this research is happening

  • University of Arizona
    Tucson, United States
    Active

Researchers

  • Principal investigator: Badger, Terry a — University of Arizona
  • Study coordinator: Badger, Terry a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.