Thinking skills and self-care after a liver transplant
Cognitive Function, Self-Management, and Health Outcomes among Liver Transplant Recipients: the LivCog Cohort
['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-11398886
This project follows people who received liver transplants to learn how changes in thinking and memory affect managing medicines, clinic visits, and overall health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-11398886 on ClinicalTrials.gov |
What this research studies
If you join, you would have regular tests of memory, attention, and problem-solving, plus questionnaires about taking medicines and handling daily health tasks. The team will review your medical records, track hospital visits and lab results, and follow these measures over time after transplant. They will also collect information about age, alcohol history, other health problems, and caregiver support to see how these affect thinking and self-care. The goal is to understand who may need extra support to stay healthy after a liver transplant.
Who could benefit from this research
Good fit: Adults who have recently received a liver transplant and can complete cognitive testing, questionnaires, and medical follow-up are the ideal participants.
Not a fit: People without a liver transplant, those outside the recruitment window, or those unable to attend follow-up visits or complete testing would not be eligible and likely would not benefit directly.
Why it matters
Potential benefit: If successful, this work could help doctors identify transplant patients who need extra cognitive or self-management support to prevent complications.
How similar studies have performed: Prior studies show cognitive problems are common in liver disease before transplant, but long-term, detailed tracking after transplant is relatively limited, making this cohort approach somewhat novel.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SERPER, MARINA — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: SERPER, MARINA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alcoholic Liver Diseases