NIH-funded research NIH-funded research

Integrated self-management support for asthma and depression in older adults

Official title: Integrated Intervention for Depression and Asthma Self-management in Older Adults

Funded at Icahn School of Medicine at Mount Sinai · NIH-11417988 · Data updated 2026-11-12

A program that combines asthma self-management with depression-focused therapy to help older adults control asthma and feel better.

More Depression research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 15, 2025
Project endAugust 31, 2028
Funding year2026
Award (this year)$242,502
NIH project number5R34HL179141-02
Project IDNIH-11417988 on NIH RePORTER

Who could benefit from this research

Could help

Older adults (typically 60+) with asthma and co-occurring depressive disorders who have uncontrolled asthma despite standard management.

Less likely to help

Patients without both asthma and depressive disorders or those with well-controlled asthma may see little to no benefit.

What this research studies

This project aims to help older adults who have both asthma and depression by combining an existing asthma self-management program with a cognitive behavioral therapy approach for adherence and mood. Researchers will develop a 10-12 session integrated program with input from patients and caregivers, then test its feasibility and potential to improve both asthma control and depressive symptoms. The team will run a small randomized trial to see if the integrated approach works better than usual care for this group. The work engages patients in shaping the content to meet their needs and preferences.

Why it matters

Potential benefit: If successful, patients could experience better asthma control and reduced depressive symptoms, leading to fewer hospital visits and a higher quality of life.

How similar studies have gone: Earlier SAMBA work showed benefits for asthma adherence, though it was less effective in patients with depression; CBT-AD has shown promise for chronic disease and depression, suggesting potential synergy.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: Wisnivesky, Juan P — Icahn School of Medicine at Mount Sinai
  • Study coordinator: Wisnivesky, Juan P

Related research

Other NIH-funded projects on the same topics.

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    NIH research Texas Woman's University · Denton, United States · NIH-10973811

  • A mobile health tool to help adolescents manage asthma.

    This study is testing a new smartphone app that helps kids aged 12 to 15 manage their asthma better by working together with their caregivers to set goals and track their progress.

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  • Biotype-based Personalization of Antidepressant Augmentation in Late-Life Depression

    A multi-site study will test a computer-guided approach to choosing the best augmentation option for older adults with treatment-resistant depression.

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  • GLP-1 receptor agonists as immune targets to treat asthma in lean and obese adults

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    NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11616517

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.