Self-care support for teens and young adults with sickle cell

Self-Management for Youth Living with Sickle Cell Disease (SMYLS)

NIH-funded research Medical University of South Carolina · NIH-11285152

A smartphone-based self-care program helps adolescents and young adults with sickle cell disease build everyday management skills as they move to adult care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-11285152 on NIH RePORTER

What this research studies

You would use a smartphone app that gives education, reminders, and tools to help with medicines, symptom tracking, and planning care. The team will enroll adolescents and young adults with sickle cell, track how much you use the app, and compare self-management behaviors before and after using it. They will also measure your patient activation (confidence and readiness to manage health) to see how it relates to behavior changes and health service use. Results will inform a clinical care model and resources for patients and providers.

Who could benefit from this research

Good fit: Adolescents and young adults (about 14–21 years old) with diagnosed sickle cell disease, especially those preparing to move from pediatric to adult care.

Not a fit: Infants and very young children, people already established in adult sickle cell care, or those without smartphone access or ability to use mobile apps may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this could improve daily self-care, reduce complications and emergency visits, and make the transition to adult care smoother.

How similar studies have performed: Similar mobile health self-management programs for chronic illnesses and small pilot studies in sickle cell have shown promise, but larger rigorous trials are still limited.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.