Improving medication adherence and blood pressure control in older African Americans

OPtimizing Technology to Improve Medication Adherence and Blood Pressure Control

Not applicable Interventional Case Western Reserve University · NCT05293756

This study is testing a new technology-based program to help older African Americans better manage their high blood pressure and improve their overall health.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment208 (estimated)
Ages50 Years and up
SexAll
SponsorCase Western Reserve University Academic / other
Locations1 site (Cleveland, Ohio)
Trial IDNCT05293756 on ClinicalTrials.gov

What this trial studies

OPTIMA-BP is an interventional study that evaluates a technology-based approach to enhance self-management of hypertension among older African Americans. The study involves a 12-month randomized control trial comparing the intervention group with a waitlist control group, focusing on systolic blood pressure and health-related quality of life. It also examines the role of knowledge, self-efficacy, and social support in managing hypertension. Qualitative evaluations will be conducted to identify barriers and strengths of the intervention for future improvements.

Who should consider this trial

Good fit: Ideal candidates are African American individuals aged 50 and older who have hypertension and are prescribed multiple antihypertensive medications.

Not a fit: Patients who have experienced a major cardiovascular event in the past year or have chronic kidney disease may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better blood pressure control and improved quality of life for older African Americans with hypertension.

How similar studies have performed: Other studies have shown promise in using technology for hypertension management, indicating that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Self-identify as African American
2. 50 years of age or older
3. Diagnosed with hypertension, with a systolic blood pressure≥ 130 mmHg but less than 170 mmHg
4. Prescribed at least two hypertensive, one of which is a diuretic/thiazide and or calcium channel blocker antihypertensive medication
5. Own a smartphone with a data plan, the capability to download the Medisafe app, or view videos
6. Able to read/understand English

Exclusion Criteria:

1. Unable to give informed consent or judged to have impaired cognitive ability or severe memory
2. Currently using a medication management application (app)
3. Experienced a major CVD event or procedure (e.g., myocardial infarction, stroke, heart surgery) within the past year
4. Patients with a diagnosis of chronic kidney disease (defined as estimated glomerular filtration rate (eGFR) \< 60 ml/min/1.73m2) and/or receiving dialysis.

Where this trial is running

Cleveland, Ohio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HypertensionSelf-ManagementTechnologyQuality of LifeHome Blood Pressure Monitoring
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.