NIH-funded research R21 grant

AI-powered, person-centered chatbot to help manage menstrual pain

Official title: AI-Supported, Evidence-based, Person-Centered Chatbot for Dysmenorrhea Self-Management: Further Development and Preliminary Evaluation

Funded at University of Arizona · NIH-11436001 · Data updated 2026-11-12

A patient-friendly AI chatbot called PeriodPal will provide evidence-based, personalized tips to help manage dysmenorrhea and reduce days missed from work or school.

More Self-management research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Arizona
NIH-funded
Lab location1 site (Tucson, United States)
Project startSeptember 11, 2026
Project endAugust 31, 2028
Funding year2026
Award (this year)$418,257
NIH project number1R21HD123835-01
Project IDNIH-11436001 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older experiencing dysmenorrhea who are seeking self-management guidance through a digital tool.

Less likely to help

Individuals who do not experience moderate to severe menstrual pain or who prefer non-digital self-management approaches may not benefit.

What this research studies

Dysmenorrhea affects a large portion of people who menstruate and disrupts daily activities. This project will refine and test an AI-assisted chatbot that delivers tailored, evidence-based self-management guidance for menstrual pain, with 24/7 real-time support. The team will assess how feasible and user-friendly PeriodPal is for adults 21 and older, using interactive modules and safe, expert information to support daily self-care. The goal is to empower patients to manage symptoms more effectively and improve quality of life.

Why it matters

Potential benefit: If successful, patients could experience better control of menstrual pain and fewer missed days from work or school through personalized digital support.

How similar studies have gone: Previous digital health tools for pain self-management have shown promise, but AI-informed, personalized chatbots for dysmenorrhea are emerging and require feasibility testing.

Where this research is happening

  • University of Arizona
    Tucson, United States
    Active

Researchers

  • Principal investigator: Chen, Chen X — University of Arizona
  • Study coordinator: Chen, Chen X

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.