Condition

Postpartum clinical trials and research

• 30Clinical trials
• 229NIH research projects
• 1New in 30 days
• 19Countries

Newest Postpartum clinical trials

All recruiting trials (30)

• Smartphone-supported single-session psychotherapy for postpartum depression

  A single online therapy session plus four weeks of app-based support is being tested to see if it reduces depressive symptoms in postpartum women compared with a waitlist.

  Recruiting University of Sao Paulo · São Paulo, São Paulo · NCT07925762

• Reducing Chronic Pain After Cesarean Delivery

  A single-session pain-relief class called Empowered Relief is tested alongside standard postpartum care to see if it helps women who have ongoing pain after cesarean delivery.

  Recruiting Stanford University · Palo Alto, California · NCT07799883

• Doula-delivered postpartum support with nurse coordination for people with preterm births in the NICU

  This trial tests whether doula-delivered postpartum help, guided by nurses, improves health outcomes and experiences for people with babies under 34 weeks in the NICU, compared to standard postpartum care.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT07787845

• Postpartum Exercise Program to Improve Neuromuscular Health and Wellbeing

  A postpartum women’s eight-week, clinician-guided exercise program tests whether structured activity improves muscle strength, pelvic floor function, daily activity, and wellbeing.

  Recruiting Carroll University · Waukesha, Wisconsin · NCT07613333

• Hypopressive versus transversus abdominis core training for postpartum urinary leakage

  This test will see if hypopressive breathing exercises or transversus abdominis-focused core training better reduces urinary leakage and improves pelvic floor function and quality of life in postpartum women.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT07576283

• Postpartum pelvic floor recovery and early rehabilitation after vaginal birth

  This project tests whether early, individualized pelvic floor muscle training starting 2–3 weeks after a vaginal birth helps people with postpartum pelvic floor symptoms recover better than usual care.

  Recruiting at 2 sites Vastra Gotaland Region · Gothenburg and 1 other locations · NCT07430865

• Radiofrequency diathermy for postpartum abdominal muscle separation

  This test will see if a single session of radiofrequency diathermy changes pain sensitivity and tissue elasticity in postpartum women with or without rectus abdominis diastasis.

  Recruiting University of Valencia · Valencia, Valencia · NCT07419399

• Support for the transition to Parenthood with Online Sex and Relationship Knowledge

  This program tests STORK, an online resource aimed at helping expecting couples manage sexual well-being during the transition to parenthood.

  Recruiting at 2 sites Dalhousie University · Vancouver, British Columbia and 1 other locations · NCT07344454

• Hope‑D digital weight management program for pregnancy and the first six months after birth

  This test tries the Hope‑D digital weight management program with pregnant women who had a pre-pregnancy BMI of 30 or higher to support weight during pregnancy and through six months postpartum.

  Recruiting Turku University Hospital · Turku, Finland · NCT07272824

• National insurance funding to increase vaccination in outpatient care

  This project will try giving vaccines paid for by the national health insurance in outpatient visits at several hospitals to see if it raises pertussis vaccination in pregnant women and pneumococcal vaccination in eligible adults.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris, IDF and 5 other locations · NCT07243236

• Crowning time and levator ani muscle detachment after a first vaginal birth

  We will see if the length of time the baby's head is crowning during labor is linked to levator ani muscle detachment in first-time moms who have a spontaneous vaginal birth.

  Recruiting Université de Sherbrooke · Sherbrooke, Quebec · NCT07210788

• Best duration for postpartum remote blood pressure monitoring

  This tests whether 2 weeks or 6 weeks of remote blood pressure monitoring after delivery works better for people who had hypertensive disorders of pregnancy.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT07204756

• MSC exosome treatment to repair blood vessel damage after preeclampsia

  This study will see if IV infusions of mesenchymal stem cell–derived exosomes help repair damaged blood vessels in women who recently had preeclampsia.

  Recruiting Phase 1/2 Universitas Padjadjaran · Bandung, West Java · NCT07183384

• Short course of low‑dose heparin to prevent postpartum blood clots

  This study will test whether a short 7–10 day course of low‑dose low‑molecular‑weight heparin after delivery reduces blood clots and how it affects bleeding and wound problems in postpartum women with certain risk factors.

  Recruiting at 9 sites Phase 3 University Hospital, Geneva · Baden and 8 other locations · NCT07140211

• Organ dysfunction score for pregnant and early postpartum patients

  This project will test a pregnancy‑adjusted SOFA score (SOFA-OBS) and whether pulse oximeter oxygenation can replace arterial measures to predict mortality in pregnant or up to 3-day postpartum adults admitted to the ICU.

  Recruiting at 11 sites Argentinian Intensive Care Society · Avellaneda, Buenos Aires and 17 other locations · NCT07068022

• MOVIN: a virtual program to support mental health during pregnancy and the early months after birth.

  This project will test a virtual collaborative-care program called MOVIN to see if it reduces depression and anxiety in pregnant and postpartum people with infants up to 6 months old who have elevated symptoms.

  Recruiting at 2 sites Women's College Hospital · Toronto, Ontario and 1 other locations · NCT07066631

• Using bedside transperineal ultrasound to give visual feedback during pelvic floor exercises after childbirth

  This trial will test whether showing postpartum women live ultrasound images of their pelvic floor helps them do pelvic floor exercises more correctly and stay more engaged after a vaginal birth.

  Recruiting Singapore General Hospital · Singapore · NCT07065708

• Mediterranean Diet program for postpartum heart and metabolic health

  This project tests whether teaching pregnant women with obesity, high blood pressure, or diabetes to follow a Mediterranean Diet helps improve their heart and metabolic health after birth.

  Recruiting Universidade do Porto · Porto, Viana do Castelo District · NCT07038681

• Laughter therapy for mothers' well-being and attachment

  This study is testing whether laughter therapy can help new mothers feel happier and improve their relationships during the first year after giving birth.

  Recruiting Selcuk University · Konya, Selçuklu · NCT06917417

• Visual education tool to help postpartum first-time mothers recognize urgent warning signs

  This project will test whether a simple picture-based education tool helps first-time English-speaking postpartum mothers recognize and report urgent maternal warning signs.

  Recruiting Northwestern University · Chicago, Illinois · NCT06912776

• Understanding parental well-being after childbirth in Switzerland

  This study looks at how new parents in Switzerland feel and cope during the first year after having a baby to see how postnatal care can be improved.

  Recruiting at 2 sites School of Health Sciences Geneva · Geneva and 1 other locations · NCT06886841

• Promoting healthy diet and activity after pregnancy for migrant women with a smartphone app

  A smartphone app called PRIMI is being tested to help first-generation migrant women after birth eat better and stay active.

  Recruiting Linkoeping University · Linköping, Östergötland County · NCT06881277

• Rivaroxaban in breast milk after maternal dosing

  This will test how much rivaroxaban passes into breast milk in postpartum people taking either prophylactic (10 mg) or therapeutic (20 mg) doses.

  Recruiting Phase 1 Thomas Jefferson University · Philadelphia, Pennsylvania · NCT06831474

• Baby swimming to help new mothers with depression and attachment issues

  This study tests whether baby swimming can help new moms with depression feel better and build a stronger bond with their babies.

  Recruiting Uppsala University · Uppsala · NCT06807801

• Using external trigeminal nerve stimulation to treat migraines in pregnant women

  This study is trying to see if a device that stimulates a nerve in the face can safely help pregnant women with migraines feel better.

  Recruiting Cefaly Technology · Darien, Connecticut · NCT06788977

• Improving postpartum-to-primary care transitions for people with chronic conditions

  This study tests whether embedding default PCP appointments, tailored reminder messages, and care recommendations into routine inpatient postpartum care helps people with chronic conditions connect with primary care after delivery.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT06557005

• Comparing breathing and pelvic exercises for postpartum pelvic pain relief

  This study is testing whether breathing exercises or pelvic stabilization exercises can help new mothers with pelvic pain feel better and improve their quality of life.

  Recruiting National Cheng Kung University · Tainan, Taiwan · NCT06284278

• Evaluating drug excretion in breast milk after cimetidine administration

  This study tests how the drug cimetidine passes into breast milk in healthy new mothers to see if genetics affect how it's transported.

  Recruiting Phase 4 University of Washington · Seattle, Washington · NCT06056583

• Mobile app to promote exercise for pregnant women

  This study is testing if a mobile app can help pregnant and new moms in rural areas exercise more and improve their overall health compared to just getting an informational brochure.

  Recruiting Western Kentucky University · Bowling Green, Kentucky · NCT05849649

• Comparing high-intensity and moderate-intensity exercise during pregnancy and its effects on health and birth outcomes

  This study tests whether high-intensity or moderate-intensity exercise during pregnancy can improve health and birth outcomes for moms and their babies.

  Recruiting Gdansk University of Physical Education and Sport · Gdansk, Pomeranian Voivodeship · NCT05009433

NIH-funded research (newest 40 of 229)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Wearable tech to track blood loss during childbirth

  A wearable device monitors cardiovascular signals to detect postpartum hemorrhage early so clinicians can act quickly to protect mothers.

  NIH research Washington University · Saint Louis, United States · NIH-11627926

• HIV treatment and postpartum weight help after birth in South Africa

  A small, patient-friendly study is testing a lay health worker–led program to support postpartum women living with HIV in staying on ART and managing weight.

  NIH research Hartford Hospital · Hartford, United States · NIH-11625634

• HIV-positive mothers in South Africa: a first look at keeping HIV treatment and healthy postpartum weight

  A small, lay health worker–led pilot aims to help postpartum women living with HIV stay on treatment and manage weight to improve health after birth.

  NIH research Hartford Hospital · Hartford, United States · NIH-11624837

• Group-based postpartum depression prevention: in-person vs. virtual delivery

  A large study is testing whether the ROSE group program delivered virtually to pregnant people is just as helpful as the in-person version in preventing postpartum depression.

  NIH research University of Denver (Colorado Seminary) · Denver, United States · NIH-11606534

• Improving contraception decisions for women with substance use disorders after childbirth

  A patient-centered decision tool called MyPath aims to help postpartum women with substance use disorders choose and keep effective contraception after giving birth.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11601588

• CREBRF gene and diabetes risk in American Samoan pregnancies

  This project follows 350 pregnant American Samoan women to understand how a specific gene variant may influence diabetes risk during and after pregnancy.

  NIH research Yale University · New Haven, United States · NIH-11592385

• Collaborative mental health care for HIV-positive pregnant and postpartum women in Kenya

  A project tests a team-based approach to treat depression and anxiety for pregnant and new mothers with HIV in Kenya, using existing clinic staff and a low-intensity therapy.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11578570

• Integrated group postpartum and well-child care to improve maternal and infant health

  A Johns Hopkins study will test a new postpartum and well-child care model delivered in group settings to improve health outcomes for mothers and their babies in low-resource settings.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11559955

• Postpartum depression screening at well-child visits in Arkansas

  A study examines whether adding depression screening at baby visits in Arkansas improves detection and care for new mothers.

  NIH research Univ of Arkansas for Med Scis · Little Rock, United States · NIH-11550534

• Maternal Postpartum Monitoring with a Wearable Sensor (MOMS)

  A wearable system called MOMS will continuously monitor multiple physiological signals in pregnant people to detect postpartum hemorrhage earlier than standard vital signs.

  NIH research University of California-Irvine · Irvine, United States · NIH-11536966

• Healthy Families-PrEP: helping women in Uganda start and stay on PrEP during periconception, pregnancy, and postpartum

  A program in Uganda helps periconception, pregnant, and postpartum women use PrEP safely to prevent HIV, with support sessions and monitoring.

  NIH research Yale University · New Haven, United States · NIH-11533806

• Ketamine to reduce postpartum depression and pain after cesarean delivery

  This grant explores a ketamine approach to help new mothers after cesarean delivery feel better sooner and with less pain.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11509433

• Community health workers to improve postpartum diabetes screening in Indian urban slums

  A program using community health workers in Pune, India to boost postpartum diabetes screening for women who had gestational diabetes.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11478531

• Community health workers to boost postpartum diabetes screening in India's urban slums

  A large study in India tests whether community health workers can help new mothers get screened for type 2 diabetes after gestational diabetes, either at home or via clinic referrals.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11478530

• Healthy Families-PrEP: helping pregnant and new mothers in Uganda stay HIV-free

  A family-focused program in Uganda tests an approach to help women who are planning pregnancy or are pregnant or postpartum use PrEP to prevent HIV infection.

  NIH research Yale University · New Haven, United States · NIH-11473991

• Pregnancy, breastfeeding, and immune changes in postpartum breast cancer

  This research tests whether breast changes after pregnancy make postpartum breast cancer more aggressive and whether breastfeeding or common anti-inflammatory medicines might lower that risk for women who recently gave birth.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11473210

• LA-MOM: Long-Acting HIV ART in Pregnancy and After Birth

  This study follows pregnant people with HIV who receive long-acting injectable HIV medicines to understand how the drugs behave in the body, how they reach the baby, and what patients experience during pregnancy and after birth.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11470920

• Injectable HIV PrEP in maternity clinics to protect pregnant and postpartum women

  A doctor-scientist team is testing a twice-yearly injectable HIV prevention medicine for pregnant and postpartum women in high-risk areas to help keep them and their babies HIV-free.

  NIH research University of Washington · Seattle, United States · NIH-11470489

• Stepped care to improve PrEP use for pregnant and breastfeeding women in South Africa

  This project offers a stepped approach to help pregnant and breastfeeding women in South Africa start and keep using HIV prevention medicine (PrEP).

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11459364

• Trajectories of Positive Motivation and Postpartum Depression Risk

  This project studies how brain reward function and daily mood patterns before and after birth relate to the risk of postpartum depression, with a focus on mothers and babies.

  NIH research Vanderbilt University · Nashville, UNITED STATES · NIH-11458939

• Effects of prescription opioid use during pregnancy on a mother's brain after birth

  This project looks at how taking prescription opioids during pregnancy changes a mother's brain and behavior after her baby is born.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11457183

• AI-powered real-time postpartum hemorrhage risk predictor in clinical care

  A real-time AI tool integrated into electronic health records helps identify women at risk for postpartum hemorrhage so clinicians can intervene earlier.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11448238

• Targeting Ubiquitination to Improve Uterotonic Therapies in Postpartum Hemorrhage

  A new approach aims to boost uterine contractions during childbirth and after delivery by understanding how a hormone receptor is regulated, potentially reducing postpartum hemorrhage risk.

  NIH research Washington University · Saint Louis, United States · NIH-11442951

• PrEP in Pregnancy and Postpartum Data Hub

  A patient-friendly data-sharing project that brings together information from many pregnancy and postpartum PrEP studies to better understand HIV prevention for mothers and their babies.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11441388

• Family sodium reduction program for new mothers with hypertensive pregnancy disorders

  A postpartum care program helps women with hypertensive disorders of pregnancy reduce salt in their diet to lower blood pressure and protect heart health.

  NIH research Vanderbilt University · Nashville, UNITED STATES · NIH-11438407

• Scalable, quick digital help for new mothers with intrusive postpartum thoughts

  A brief, self-guided digital session helps new parents understand and reduce distress from unwanted postpartum thoughts.

  NIH research Mclean Hospital · Belmont, United States · NIH-11438134

• Tailored postpartum care strategies to improve maternal health

  A real-world study tests a customized set of postpartum care practices led by community partners to improve new mothers' health and safety.

  NIH research Thomas Jefferson University · Philadelphia, United States · NIH-11433740

• A community-driven plan to prevent severe pregnancy complications and improve family health

  A community-led project to understand severe maternal morbidity from the patient and family perspective and create local strategies to keep mothers and babies healthier.

  NIH research New York University · New York, United States · NIH-11423704

• Personalized Postpartum Bleeding Risk Prediction with Machine Learning and Genetic Scores

  This grant aims to create a personalized tool that predicts a mother’s risk of postpartum hemorrhage using machine learning and her genetic information.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11419168

• ROSE Scale-Up: Expanding universal postpartum depression prevention for new mothers

  A national effort to roll out the ROSE prevention program to all new mothers, to see if universal use can reduce postpartum depression.

  NIH research Michigan State University · East Lansing, United States · NIH-11417516

• Integrated postpartum and well-child care model to improve maternal and child health

  A Johns Hopkins team is testing a group-based postpartum and well-child care model to help mothers and babies in low-resource settings feel healthier and supported in the first year after birth.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11416489

• OVAL: How laws about drug use in pregnancy affect pregnant and new mothers who use drugs

  A nationwide project is looking at how laws about drug use in pregnancy influence health for pregnant and postpartum women who use drugs.

  NIH research Morehouse School of Medicine · Atlanta, United States · NIH-11415769

• Maternal heart health starts at home: Targeting social needs to improve pregnancy and postpartum heart health

  Aimed at improving heart health for pregnant and postpartum people by addressing social needs like housing and access to care.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11415084

• Optimal timing to pause GLP-1 receptor therapy before pregnancy

  This grant aims to figure out the best waiting period after stopping GLP-1 receptor medications to have a healthy pregnancy and baby.

  NIH research Northwestern University · Chicago, United States · NIH-11413873

• Community health workers to boost postpartum diabetes screening in urban India

  A study tests whether community health workers can help women in Indian slums get screened for type 2 diabetes after pregnancy.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11413769

• Partnering with pregnant people to create a new plan to cut tobacco and cannabis use

  A community-driven project with pregnant and postpartum women to design a tailored approach for reducing tobacco and cannabis use during and after pregnancy.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11412943

• We Are Together: a community program to reduce HIV stigma among pregnant and postpartum women

  A patient-facing program in Ghana and the United States aims to reduce HIV-related stigma for pregnant and postpartum women to help them stay on treatment and feel better.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11411174

• Empowering postpartum care in the Mississippi Delta

  A multisector program helps pregnant and new mothers in the Mississippi Delta access and benefit from postpartum care through better information, trusted care coordination, and insured, affordable services.

  NIH research Jackson State University · Jackson, United States · NIH-11408712

• MOMS Postpartum coaching for CHWs to support new mothers

  A free online training helps community health workers better support new mothers after birth to reduce health problems.

  NIH research Kdh Research and Communication, INC. · Atlanta, UNITED STATES · NIH-11407484

• OPTIMUM OB-TXA: Timing, route, and dose of tranexamic acid to prevent postpartum bleeding before cord clamping

  Aims to find the best time, method, and amount of tranexamic acid given before cord clamping to prevent postpartum hemorrhage in new mothers and protect babies.

  NIH research Inova Health Care Services · Fairfax, UNITED STATES · NIH-11404879

Related topics

Quick answers

How many Postpartum clinical trials are recruiting right now?

30, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 19 countries. The most sites are in United States (10 trials), Sweden (3 trials), Canada (3 trials), Switzerland (2 trials), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Phase 1: 1, Phase 1/2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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