ROSE Scale-Up: Expanding universal postpartum depression prevention for new mothers
Official title: The ROSE Scale-Up Study: Informing a decision about ROSE as universal postpartum depression prevention
Funded at Michigan State University · NIH-11417516 · Data updated 2026-11-12
A national effort to roll out the ROSE prevention program to all new mothers, to see if universal use can reduce postpartum depression.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project start | September 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,249,953 |
| NIH project number | 5R01MH130948-05 |
| Project ID | NIH-11417516 on NIH RePORTER |
Who could benefit from this research
✓Could help
New mothers, regardless of identified risk factors, in participating clinics and communities.
✕Less likely to help
Women not enrolled in participating sites or who do not experience PPD may not see direct benefit.
What this research studies
This project builds on the ROSE program, an evidence-based approach to prevent postpartum depression. It tests whether offering ROSE universally in healthcare and community settings is feasible and effective, rather than only to high-risk women. Researchers will use electronic health records, enroll participants, and monitor outcomes to determine impact and cost. The study involves real-world settings and aims to inform decisions about making universal prevention a standard practice for new mothers.
Why it matters
Potential benefit: If successful, universal ROSE could lower postpartum depression rates and improve maternal and infant well-being.
How similar studies have gone: Previous ROSE trials showed strong prevention effects in targeted groups; universal prevention is being tested for broader impact.
Where this research is happening
-
Michigan State University
East Lansing, United States Active
Researchers
- Principal investigator: Johnson, Jennifer E — Michigan State University
- Study coordinator: Johnson, Jennifer E
Related research
Other NIH-funded projects on the same topics.
-
Group-based postpartum depression prevention: in-person vs. virtual delivery
A large study is testing whether the ROSE group program delivered virtually to pregnant people is just as helpful as the in-person version in preventing postpartum depression.
-
Postpartum depression screening at well-child visits in Arkansas
A study examines whether adding depression screening at baby visits in Arkansas improves detection and care for new mothers.
-
Ketamine to reduce postpartum depression and pain after cesarean delivery
This grant explores a ketamine approach to help new mothers after cesarean delivery feel better sooner and with less pain.
-
Trajectories of Positive Motivation and Postpartum Depression Risk
This project studies how brain reward function and daily mood patterns before and after birth relate to the risk of postpartum depression, with a focus on mothers and babies.
-
How Medicaid Postpartum Coverage and PPD Screening Could Improve Diabetes and Blood Pressure Care After Birth
A large NIH grant is studying how extending Medicaid after birth and mandating postpartum depression screening affect care for women with gestational diabetes and pregnancy-related high blood pressure.
-
Virtual group care to prevent postpartum depression in immigrant Latinas
A federally funded program tests a virtual group, based on CBT and attachment theory, to help pregnant women and new mothers from immigrant Latina communities reduce postpartum depression symptoms.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.