NIH-funded research R01 grant

Collaborative mental health care for HIV-positive pregnant and postpartum women in Kenya

Official title: Integration of a collaborative care model for mental health services into HIV care for pregnant and postpartum women in Kenya (the Tunawiri Study)

Funded at University of Colorado Denver · NIH-11578570 · Data updated 2026-11-12

A project tests a team-based approach to treat depression and anxiety for pregnant and new mothers with HIV in Kenya, using existing clinic staff and a low-intensity therapy.

More Mental Health research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startAugust 1, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$218,649
NIH project number3R01MH133260-04S1
Project IDNIH-11578570 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are pregnant or up to postpartum women living with HIV in Kenya who experience symptoms of depression or anxiety.

Less likely to help

Individuals without mental health symptoms or those outside the target perinatal period may not benefit from this intervention.

What this research studies

This study will embed a collaborative care model into routine antenatal and HIV services in Kenya to treat common mental disorders among pregnant and postpartum women living with HIV. It uses a low-intensity therapy plus care management, supported by a consultant psychiatrist, and leverages peer mentors and non-specialist staff to deliver care. The project will also examine costs and cost-effectiveness to inform scale-up within real-world health systems, guided by the EPIS framework to plan for sustainability. The goal is to improve mental health, HIV care engagement, and ultimately maternal and child health outcomes in this population.

Why it matters

Potential benefit: If successful, this approach could improve mental health and HIV outcomes for pregnant and postpartum women with HIV in Kenya and provide a scalable model for LMIC settings.

How similar studies have gone: There is prior evidence that collaborative care models can improve CMD outcomes and be feasible in LMIC settings, with this study aiming to adapt and scale within perinatal HIV care.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Abuogi, Lisa Lynn — University of Colorado Denver
  • Study coordinator: Abuogi, Lisa Lynn

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.