PrEP in Pregnancy and Postpartum Data Hub
Official title: The PrEP in Pregnancy and Postpartum (P3) Data Hub
Funded at Univ of North Carolina Chapel Hill · NIH-11441388 · Data updated 2026-11-12
A patient-friendly data-sharing project that brings together information from many pregnancy and postpartum PrEP studies to better understand HIV prevention for mothers and their babies.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | September 14, 2026 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $155,500 |
| NIH project number | 1R03HD123302-01 |
| Project ID | NIH-11441388 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are pregnant or postpartum individuals who are considering PrEP or have used PrEP during pregnancy or after birth and are willing to share related study data.
✕Less likely to help
People outside the pregnancy/postpartum window or those not involved in PrEP research may not see direct benefits.
What this research studies
This project will unite data from 19 PrEP studies involving pregnant and new mothers to enable clearer analyses of safety, effectiveness, and use during pregnancy and after birth. It will establish strong data governance, including consent, privacy, and data sharing rules, so researchers can use the information responsibly. By harmonizing details like drug levels, maternal and infant outcomes, and prevention efficacy, doctors can gain more reliable insights to guide care for HIV prevention in pregnancy. The work is led by the University of North Carolina at Chapel Hill and collaborators to create a robust resource for future research and ultimately better outcomes for mothers and infants.
Why it matters
Potential benefit: If successful, the data hub could improve guidance on PrEP use during pregnancy/postpartum to reduce HIV risk for mothers and their babies.
How similar studies have gone: Previous PrEP studies in pregnancy/postpartum have generated data but a centralized hub is expected to enhance power and applicability of findings.
Where this research is happening
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Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Chi, Benjamin H. — Univ of North Carolina Chapel Hill
- Study coordinator: Chi, Benjamin H.
Related research
Other NIH-funded projects on the same topics.
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Healthy Families-PrEP: helping women in Uganda start and stay on PrEP during periconception, pregnancy, and postpartum
A program in Uganda helps periconception, pregnant, and postpartum women use PrEP safely to prevent HIV, with support sessions and monitoring.
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Healthy Families-PrEP: helping pregnant and new mothers in Uganda stay HIV-free
A family-focused program in Uganda tests an approach to help women who are planning pregnancy or are pregnant or postpartum use PrEP to prevent HIV infection.
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CREBRF gene and diabetes risk in American Samoan pregnancies
This project follows 350 pregnant American Samoan women to understand how a specific gene variant may influence diabetes risk during and after pregnancy.
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Adaptation of a problem-solving approach to boost PrEP use during pregnancy in Zimbabwe
A multi-level program is being adapted to help pregnant and postpartum women in Zimbabwe start and stick with HIV PrEP, with support from providers and communities.
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LA-MOM: Long-Acting HIV ART in Pregnancy and After Birth
This study follows pregnant people with HIV who receive long-acting injectable HIV medicines to understand how the drugs behave in the body, how they reach the baby, and what patients experience during pregnancy and after birth.
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Injectable HIV PrEP in maternity clinics to protect pregnant and postpartum women
A doctor-scientist team is testing a twice-yearly injectable HIV prevention medicine for pregnant and postpartum women in high-risk areas to help keep them and their babies HIV-free.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.