MOVIN: a virtual program to support mental health during pregnancy and the early months after birth.
The Pregnancy and Postpartum Mental Health Optimization Virtual Intervention Network (MOVIN): Randomized Controlled Trial
This project will test a virtual collaborative-care program called MOVIN to see if it reduces depression and anxiety in pregnant and postpartum people with infants up to 6 months old who have elevated symptoms.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 570 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Women's College Hospital Academic / other |
| Locations | 2 sites (Toronto, Ontario and 1 other locations) |
| Trial ID | NCT07066631 on ClinicalTrials.gov |
What this trial studies
MOVIN delivers stepped, collaborative mental health care online, pairing participants with a care coordinator who co-develops personalized treatment plans and liaises with primary care clinicians and perinatal psychiatrists as needed. Eligible Ontario participants with elevated symptoms are randomized 1:1 to receive the MOVIN platform or enhanced usual care and are followed with systematic, measurement-based symptom tracking. The primary outcome is depressive symptoms measured by the Edinburgh Postnatal Depression Scale at 24 weeks post-randomization, with symptom remission (EPDS <10) as a main secondary outcome. The platform includes curated education, treatment resources, and direct referral pathways to support scalable perinatal mental health care.
Who should consider this trial
Good fit: Ideal candidates are adults in Ontario who are pregnant or the primary parent of an infant 0–6 months old, have an EPDS score above 10, and can complete study activities in English and online.
Not a fit: People with active substance use disorder, mania or psychosis, an active suicide plan or intent, those planning to leave Ontario during the study, or those unable to complete online procedures are unlikely to benefit from this program.
Why it matters
Potential benefit: If successful, MOVIN could make it easier for pregnant and postpartum people to access timely, personalized mental health care and reduce depressive and anxiety symptoms.
How similar studies have performed: Collaborative care models have previously improved perinatal depression outcomes, but MOVIN's fully virtual, province-wide stepped-care delivery is a newer adaptation of that evidence base.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Adult (age 18 years or older) 2. Pregnant or postpartum and living with their infant 0-6 months old. This includes all individuals who identify as women, as well as those of female sex who do not identify as women (e.g., non-binary, trans) who are the primary parent for their infant. This includes via natural birth, adoption, or surrogacy. 3. EPDS score \>10 at eligibility screening. Exclusion Criteria: 1. Active alcohol or substance use disorder, mania or psychotic disorder (as these conditions are better managed in direct specialty care). 2. Active suicide plan or intent (as emergent hospital-based care is likely required), 3. Plan to move out of Ontario during the study. 4. Unable to complete relevant study procedures and measures online. For the few participants without access to devices/home internet, we will budget for tablets/data plans. 5. Unable to complete study activities in English. Note that Google translate is available for the intervention platform and language lines are available for participants so that they can be served in their language of choice, however we are unable to provide translations of all study assessment and questionnaire materials that participants will need to complete during the study. 6. No primary care clinician (required for collaborative mental health care delivery model). 7. Currently enrolled in a collaborative mental health care model.
Where this trial is running
Toronto, Ontario and 1 other locations
- Women's College Hospital — Toronto, Ontario, Canada (Active_not_recruiting)
- Women's College Hospital — Toronto, Ontario, Canada (Recruiting)
Study contacts
- Study coordinator: Simone Vigod
- Email: simone.vigod@wchospital.ca
- Phone: 416-323-6400
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.