Condition

Non-ischemic Cardiomyopathy clinical trials and research

• 13Clinical trials
• 4NIH research projects
• 11Countries

Newest Non-ischemic Cardiomyopathy clinical trials

All recruiting trials (13)

• See if stopping heart failure meds is safe for super-responders with non-ischemic cardiomyopathy and CRT

  This trial tests whether stopping heart failure medications is safe in patients with non-ischemic cardiomyopathy who have had a strong positive response to CRT and meet specific genetic and imaging criteria.

  Recruiting at 4 sites Phase 4 Institut d'Investigació Biomèdica de Bellvitge · L'Hospitalet de Llobregat, Barcelona and 3 other locations · NCT07851779

• Left bundle branch area pacing with multimodal guidance vs. conventional pacing for heart failure with complete left bundle branch block

  A multicenter trial tests whether using multimodal data to guide left bundle branch area pacing helps people with heart failure and complete left bundle branch block, compared with traditional biventricular pacing.

  Recruiting Second Affiliated Hospital of Nanchang University · Nanchang, Jiangxi · NCT07814612

• MRI-guided risk-based pacing for heart failure with reduced ejection fraction

  This study tests whether left bundle branch pacing without a defibrillator works as well as traditional CRT with defibrillator in people with a specific heart failure and MRI-detected low risk of scar.

  Recruiting Velammal Medical College Hospital and Research Institute · Madurai, Tamil Nadu · NCT07791407

• Cardiac MRI for risk prediction in non-dilated left ventricular cardiomyopathy

  This retrospective study will test whether findings on cardiac MRI can help predict serious heart problems in people with non-dilated left ventricular cardiomyopathy.

  Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing · NCT07351838

• Registry and biobank of non-ischemic cardiomyopathy with linked heart imaging

  This project will collect clinical data, heart images, ECGs, and blood samples from people with non-ischemic cardiomyopathy and at-risk relatives to try to build and test tools that predict arrhythmia risk and guide family screening.

  Recruiting Montreal Heart Institute · Montreal, Quebec · NCT07110818

• Longitudinal Assessment of Cardiac MRI Microstructure in Patients and Healthy People

  This study tests advanced, non-contrast and extended clinical cardiac MRI techniques to see how heart tissue features differ between people with heart disease and healthy individuals.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT07081711

• Using a new cardiac device to treat heart failure with less invasive techniques

  This study is testing a new heart device that can be implanted with less invasive methods to see if it helps people with heart failure feel better and improve heart function.

  Recruiting at 4 sites Berlin Heals GmbH · Banja Luka, Republic of Srbska and 3 other locations · NCT06920030

• Using radiotherapy to treat advanced heart failure

  This study is testing if a single low dose of radiation therapy can help people with advanced heart failure feel better and improve their heart function.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT06661876

• Study of heart conditions using advanced imaging techniques

  This study is trying to find out what causes different heart conditions in Hispanic and African American people in the Bronx by using advanced imaging techniques.

  Recruiting Montefiore Medical Center · The Bronx, New York · NCT06610019

• Registry for patients with non-ischemic cardiomyopathies

  This study is collecting information from people with non-ischemic cardiomyopathies to see how to better diagnose and manage their condition and predict potential heart rhythm problems.

  Recruiting Scientific Institute San Raffaele · Milan, Milano · NCT06607471

• Evaluating coronary microvascular dysfunction in heart failure patients

  This study is trying to see if problems with tiny blood vessels in the heart affect how well people with heart failure can improve their heart function after treatment.

  Recruiting Samsung Medical Center · Seoul · NCT06243653

• Development of advanced MRI techniques for heart disease assessment

  This study is testing new MRI techniques to see how heart tissue differs between people with heart disease and healthy individuals to improve heart assessments.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT05654272

• Registry for patients with cardiomyopathies

  This study is collecting health information and samples from people with different types of heart muscle diseases to better understand their causes and effects over time.

  Recruiting University Hospital Heidelberg · Heidelberg, Baden-Wurttemberg · NCT04265040

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Correcting cardiac microdomains to reverse non-ischemic heart failure

  A gene therapy approach targeting calcium-handling microdomains in the heart is being tested to restore heart function in a large animal model of non-ischemic cardiomyopathy.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11330515

• Better defining non-ischemic cardiomyopathy with functional mitral regurgitation to predict treatment outcomes

  The team will use advanced heart MRI to better classify people with non-ischemic cardiomyopathy and functional mitral regurgitation so doctors can predict which treatments may work best.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11319841

• Improving heart function by correcting calcium handling in heart cells

  This study is testing a new gene therapy that aims to fix how heart cells manage calcium in people with non-ischemic cardiomyopathy, using minipigs to see if improving a specific protein can help the heart work better and stay healthier.

  NIH research University of Utah · Salt Lake City, United States · NIH-11077253

• Improving treatment predictions for heart patients with mitral valve issues

  This study is looking at how to better understand and treat heart problems in people with non-ischemic cardiomyopathy and leaky heart valves, using advanced imaging techniques to help doctors choose the best treatments for each patient.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11073111

Related topics

Quick answers

How many Non-ischemic Cardiomyopathy clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (3 trials), China (2 trials), Spain (1 trial), Italy (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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