Improving treatment predictions for heart patients with mitral valve issues
Improving Phenotypic Classification and Prediction of Treatment Outcomes in Patients with Non-ischemic Cardiomyopathy and Functional Mitral Regurgitation
This study is looking at how to better understand and treat heart problems in people with non-ischemic cardiomyopathy and leaky heart valves, using advanced imaging techniques to help doctors choose the best treatments for each patient.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11073111 on NIH RePORTER |
What this research studies
This research focuses on patients with non-ischemic cardiomyopathy and functional mitral regurgitation, conditions that can lead to serious heart problems. The study aims to enhance the classification of these conditions and predict treatment outcomes using advanced cardiac magnetic resonance imaging (CMR). By analyzing heart structure and function more accurately, the research seeks to establish better criteria for selecting patients for interventions like Mitraclip therapy. This approach could lead to more personalized treatment plans and improved patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with non-ischemic cardiomyopathy and functional mitral regurgitation.
Not a fit: Patients with ischemic cardiomyopathy or those without functional mitral regurgitation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment strategies for patients with heart failure and mitral valve issues, potentially reducing mortality rates.
How similar studies have performed: Previous studies have shown that advanced imaging techniques like CMR can significantly improve the understanding and treatment of heart conditions, indicating a promising avenue for this research.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Kwon, Deborah — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Kwon, Deborah
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.