Development of advanced MRI techniques for heart disease assessment
Official title: Development of Cardiovascular Innovation Research Technologies
Run by The Cleveland Clinic · NCT05654272 · Data updated 2026-11-12
This study is testing new MRI techniques to see how heart tissue differs between people with heart disease and healthy individuals to improve heart assessments.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | The Cleveland Clinic Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Cleveland, Ohio) |
| Status | Recruiting |
| Started | September 9, 2022 |
| Main results expected | September 9, 2032 |
| Study ends | September 9, 2042 |
| Registry record updated | May 8, 2026 |
| Trial ID | NCT05654272 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older diagnosed with cardiovascular diseases.
✕Probably not a fit
Patients with contraindications to MRI or those in vulnerable populations, such as prisoners or individuals with cognitive impairments, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to enhance the understanding of cardiovascular diseases through advanced cardiac MRI techniques. It will compare myocardial microstructural phenotypes in patients with cardiovascular conditions and healthy individuals, linking these findings to cardiac structure and function. Participants will either undergo an extended clinical cardiac MRI exam or a research-focused non-contrast MRI exam, allowing for a comprehensive analysis of heart tissue characteristics. The study seeks to establish a faster and more efficient cardiac MRI protocol for clinical use.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic capabilities and treatment strategies for patients with cardiovascular diseases.
How similar studies have gone: Other studies utilizing advanced MRI techniques have shown promise in improving cardiovascular diagnostics, suggesting this approach may yield beneficial results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years of age * Provision of written informed consent * If not healthy volunteer, must be diagnosed with cardiovascular disease Exclusion Criteria: * Vulnerable populations will be excluded from this study including Prisoners * Other contraindications to CMR imaging to be determined by standard MRI protocols * Decisionally impaired (e.g., dementia or cognitive disability)
Where it's running
-
Cardiovascular Innovation Research Center
Cleveland, Ohio, United States Recruiting
Study contacts
- Study coordinator: CIRC Program Coordinator
- Email: circ@ccf.org
- Phone: 216 636-5373
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Longitudinal Assessment of Cardiac MRI Microstructure in Patients and Healthy People
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.