Clinical trial Recruiting at 1 site Observational Ages 18 and up

Development of advanced MRI techniques for heart disease assessment

Official title: Development of Cardiovascular Innovation Research Technologies

Run by The Cleveland Clinic · NCT05654272 · Data updated 2026-11-12

This study is testing new MRI techniques to see how heart tissue differs between people with heart disease and healthy individuals to improve heart assessments.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorThe Cleveland Clinic
Academic / other
Drugs / interventionsradiation
Locations1 site (Cleveland, Ohio)
StatusRecruiting
StartedSeptember 9, 2022
Main results expectedSeptember 9, 2032
Study endsSeptember 9, 2042
Registry record updatedMay 8, 2026
Trial IDNCT05654272 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older diagnosed with cardiovascular diseases.

Probably not a fit

Patients with contraindications to MRI or those in vulnerable populations, such as prisoners or individuals with cognitive impairments, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to enhance the understanding of cardiovascular diseases through advanced cardiac MRI techniques. It will compare myocardial microstructural phenotypes in patients with cardiovascular conditions and healthy individuals, linking these findings to cardiac structure and function. Participants will either undergo an extended clinical cardiac MRI exam or a research-focused non-contrast MRI exam, allowing for a comprehensive analysis of heart tissue characteristics. The study seeks to establish a faster and more efficient cardiac MRI protocol for clinical use.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic capabilities and treatment strategies for patients with cardiovascular diseases.

How similar studies have gone: Other studies utilizing advanced MRI techniques have shown promise in improving cardiovascular diagnostics, suggesting this approach may yield beneficial results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years of age
* Provision of written informed consent
* If not healthy volunteer, must be diagnosed with cardiovascular disease

Exclusion Criteria:

* Vulnerable populations will be excluded from this study including Prisoners
* Other contraindications to CMR imaging to be determined by standard MRI protocols
* Decisionally impaired (e.g., dementia or cognitive disability)

Where it's running

  • Cardiovascular Innovation Research Center
    Cleveland, Ohio, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.