Condition

Neuromuscular Diseases clinical trials and research

• 21Clinical trials
• 6NIH research projects
• 9Countries

Newest Neuromuscular Diseases clinical trials

All recruiting trials (21)

• Wearable monitoring of walking and arm movement in adults with neuromuscular or metabolic movement disorders

  This project uses a wrist/ankle wearable to continuously monitor walking and upper-limb movement in ambulant adults with neuromuscular diseases or obesity to see if digital measures like stride speed track real-life motor function.

  Recruiting Centre Hospitalier Universitaire de Liege · Liège · NCT07136844

• Precision diagnosis and therapy for rare eye and neuromuscular diseases

  This study is testing new ways to find the genetic causes of rare eye and muscle diseases to help create more personalized treatments for patients.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT06775561

• Research network for hereditary spastic paraplegia and primary lateral sclerosis

  This study is trying to learn more about hereditary spastic paraplegia and primary lateral sclerosis by enrolling people with specific types of the condition to help find better treatments and understand how these diseases progress.

  Recruiting Boston Children's Hospital · Miami, Florida and 10 other locations · NCT06553976

• Study of limb movements in patients with neuromuscular diseases

  This study is testing new technology to see how well it can track and understand limb movements in people with neuromuscular diseases compared to those without any movement issues.

  Recruiting Centre Hospitalier Universitaire de Liege · Liège, Liege · NCT06439823

• Using MSOT to Diagnose and Monitor Neuromuscular Diseases in Children

  This study is testing a new type of scan to see if it can help doctors diagnose and track the progress of neuromuscular diseases in children without needing invasive procedures.

  Recruiting Children's Hospital of Eastern Ontario · Ottawa, Ontario · NCT06438965

• Evaluating a new breathing device for patients with neuromuscular diseases

  This study is testing a new breathing device that adjusts to patients' needs to see if it helps people with neuromuscular diseases breathe better than their current equipment.

  Recruiting at 2 sites Phase 2 Guy's and St Thomas' NHS Foundation Trust · London, London and 1 other locations · NCT06339580

• Communication through a brain implant for people with locked-in syndrome

  This study is testing a brain implant that helps people with locked-in syndrome communicate by translating their brain activity into messages.

  Recruiting UMC Utrecht · Utrecht · NCT06207591

• Improving learning of a cough assistance technique in children

  This study is testing if a fun coaching program can help children, both healthy and those with neuromuscular diseases, learn a special cough technique better than just regular guidance from a physiotherapist.

  Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Brussels, Brussels Capital · NCT06190431

• Measuring physical activity in people with neuromuscular disorders

  This study is trying to see how much people with neuromuscular disorders move around by having them wear a device on their leg for a week every six months over three years.

  Recruiting Columbia University · New York, New York · NCT06084026

• Collection of leftover neuromuscular biopsy samples for research

  This study is collecting leftover muscle biopsy samples from patients with neuromuscular diseases to help researchers learn more about these conditions and how they affect the body.

  Recruiting University Hospital, Bordeaux · Bordeaux · NCT06074822

• Home polygraphy for neuromuscular patients using non-invasive ventilation

  This study is testing if doing sleep tests at home can help people with neuromuscular diseases who use non-invasive ventilation get better nighttime support for their breathing.

  Recruiting Assistance Publique - Hôpitaux de Paris · Garches · NCT05785637

• Development of a prognostic score for wheelchair seating changes

  This study is trying to create a scoring system to help determine when people with neuromuscular diseases need changes in their wheelchair seating to stay healthy and improve their quality of life.

  Recruiting Assistance Publique - Hôpitaux de Paris · Garches · NCT05785546

• Collection of samples from patients with neuromuscular diseases

  This study is collecting blood, skin, and muscle samples from people with neuromuscular diseases to help researchers learn more about these conditions in the future.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT05434572

• Assessing respiratory muscle function in children

  This study tests how strong the breathing muscles are in children with breathing problems to see if better treatments can help them breathe easier.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT05051254

• Observing neuromuscular disorders using advanced imaging techniques

  This study is testing advanced imaging techniques to see how neuromuscular disorders affect muscles and nerves over time in patients compared to healthy individuals.

  Recruiting National Taiwan University Hospital · Taipei · NCT05048862

• Assessing wheelchair positioning for patients with neuromuscular diseases

  This study looks at how sitting in a wheelchair affects posture and pain for people with neuromuscular diseases to see if better positioning can help them feel more comfortable.

  Recruiting at 2 sites Groupement Hospitalier Intercommunal du Vexin · Aincourt and 1 other locations · NCT05006859

• Understanding quality of life in patients with chronic respiratory failure

  This study looks at how different treatments for chronic respiratory failure, like non-invasive ventilation, affect the daily lives and well-being of patients.

  Recruiting Guy's and St Thomas' NHS Foundation Trust · London · NCT04236726

• Improving cough assistance for patients with neuromuscular diseases

  This study is testing better ways to use cough-assisting machines for people with neuromuscular diseases to help them breathe easier and clear mucus safely.

  Recruiting Guy's and St Thomas' NHS Foundation Trust · London, London · NCT04163198

• Assessing the impact of comorbidities on postoperative complications.

  This study looks at how having other health issues affects the chances of complications after abdominal surgery to help doctors better understand and manage risks for their patients.

  Recruiting at 37 sites Russian Federation of Anesthesiologists and Reanimatologists · Arkhangelsk and 37 other locations · NCT03945968

• Evaluating a new imaging system for pediatric respiratory diseases

  This study is testing a new imaging system to see if it can help monitor breathing in children with respiratory diseases and compare it to healthy kids.

  Recruiting University of Colorado, Denver · Aurora, Colorado · NCT03797183

• Evaluation of a new non-invasive respiratory monitor for children

  This study tests a new breathing monitor for kids to see if it works better than an older model by comparing how well it tracks their breathing.

  Recruiting Nemours Children's Clinic · Wilmington, Delaware · NCT02851043

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Scalable non-viral gene delivery for a common muscular dystrophy

  A patient-focused project tests a non-viral therapy to reduce harmful DMPK RNA in muscle because this could lessen symptoms of myotonic dystrophy type 1.

  NIH research Kinea Bio, INC. · Mukilteo, UNITED STATES · NIH-11525063

• Human iPSC NMJ models to study neuromuscular diseases

  Scientists are building patient-friendly lab models using stem cells from humans to study how neuromuscular diseases like ALS affect the connection between nerves and muscles.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11394226

• Antibody therapy to protect muscles in Duchenne and related diseases

  A small drug company is developing antibodies that target a key protein (LTBP4) to calm harmful signals in muscles affected by Duchenne muscular dystrophy and similar conditions, with a plan to test safety and dosing in people soon.

  NIH research Ikaika Therapeutics INC · Oak Park, United States · NIH-11323783

• Human nerve–muscle junctions grown from patient stem cells to model ALS and related neuromuscular diseases

  They are growing human nerve-to-muscle connections from patient stem cells to help develop better treatments for people with ALS and similar neuromuscular conditions.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11082176

• Creating a treatment for neuromuscular diseases using anti-LTBP4.

  This study is looking at a new treatment that targets a protein called LTBP4 to help improve muscle function and slow down Duchenne Muscular Dystrophy (DMD), so that patients can feel better and do more in their daily lives.

  NIH research Northwestern University at Chicago · Chicago, United States · NIH-11064924

• Using human stem cells to study communication between nerves and muscles in neuromuscular diseases.

  This study is exploring how special stem cells can help us create models of the connections between nerves and muscles, which are important for movement, to better understand diseases like ALS and find new ways to treat them.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-10727888

Related topics

Quick answers

How many Neuromuscular Diseases clinical trials are recruiting right now?

21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (5 trials), France (5 trials), United Kingdom (3 trials), Belgium (3 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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