Understanding quality of life in patients with chronic respiratory failure
Official title: Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure
Run by Guy's and St Thomas' NHS Foundation Trust · NCT04236726 · Data updated 2026-11-12
This study looks at how different treatments for chronic respiratory failure, like non-invasive ventilation, affect the daily lives and well-being of patients.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Guy's and St Thomas' NHS Foundation Trust Academic / other |
| Locations | 1 site (London) |
| Status | Recruiting |
| Started | December 19, 2019 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | June 4, 2026 |
| Trial ID | NCT04236726 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults diagnosed with chronic respiratory failure who are currently receiving specific respiratory interventions.
✕Probably not a fit
Patients under 18 years old or those with significant co-morbidities that hinder compliance with the study protocol may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the quality of life in patients suffering from chronic respiratory failure, including those with chronic obstructive pulmonary disease and neuromuscular diseases. It will utilize questionnaires to gather data on how various interventions impact the patients' daily lives and overall well-being. The study focuses on patients who are receiving treatments such as non-invasive ventilation and prolonged mechanical ventilation. By analyzing this data, the study seeks to provide insights into the effectiveness of current interventions on quality of life.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies that enhance the quality of life for patients with chronic respiratory failure.
How similar studies have gone: While this approach is observational and may not have been extensively tested in this specific context, similar studies have shown that understanding quality of life can lead to better patient outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Diagnosed with chronic respiratory failure receiving any of: * Non-invasive ventilation * Prolonged mechanical ventilation * Mechanical insufflation-exsufflation therapy Exclusion Criteria: * Aged \<18 * Significant physical or psychiatric co-morbidity that would prevent compliance with trial protocol
Where it's running
-
Guy's and St. Thomas NHS Foundation Trust
London, United Kingdom Recruiting
Study contacts
- Study coordinator: Neeraj Shah, MBBS
- Email: neeraj.shah@gstt.nhs.uk
- Phone: +442071888070
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.