Condition

Malocclusion clinical trials and research

• 17Clinical trials
• 1New in 30 days
• 14Countries

Newest Malocclusion clinical trials

All recruiting trials (17)

• FM Move: A New Method for Moving Back Teeth During Clear Aligner Therapy

  A single-group study tests a new FM method to move the canine and first molar together in people needing back-teeth movement, to see if treatment time can be shortened.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai · NCT07896369

• Digital vs. Conventional Indirect Bonding in Teens

  This study tests whether digital indirect bonding works as well as the conventional method for placing braces in teens who need treatment on both arches.

  Recruiting Azienda Ospedaliero-Universitaria Careggi · Florence · NCT07692880

• 3-D imaging of bone and root changes after moving a buccally displaced upper canine.

  This trial tests two orthodontic traction methods to see which causes less bone loss and root shortening when fixing a buccally displaced upper canine.

  Recruiting Sana'a University · Sanaa, Sana'a · NCT07399197

• Clear thermoplastic maxillary expander versus Hyrax for adolescents

  This will test whether a clear PETG thermoplastic expander with an integrated screw works as well as a Hyrax expander to widen the upper jaw in adolescents (ages 10–14) with a narrow maxilla.

  Recruiting University of Baghdad · Baghdad, Al-Rusafa, Bab Al-moadham · NCT07362160

• Facially guided digital full-mouth rehabilitation

  This approach tries a fully digital, face-guided workflow to rebuild the mouths of adults (20–45) who have bite problems, missing lower molars, and are unhappy with their smile.

  Recruiting Menoufia University · Shibīn al Kawm, Menoufia · NCT07314034

• Comparing scalloped, straight, and straight-extended trimlines for SureSmile clear aligners

  This study tests whether three different trimline designs for SureSmile clear aligners give accurate tooth movements in adults with mild-to-moderate malocclusion.

  Recruiting at 3 sites Dentsply Sirona Implants and Consumables · Fresno, California and 5 other locations · NCT07290790

• Bromelain to reduce facial swelling after jaw surgery

  This test will see if taking a daily bromelain supplement before and after orthognathic (jaw) surgery reduces facial swelling and shortens how long swelling lasts in adults.

  Recruiting University of Kentucky · Lexington, Kentucky · NCT07115212

• How enlarged adenoids affect the masseter (chewing) muscle in children using ultrasound

  Using ultrasound, researchers will see if enlarged adenoids change the thickness or internal bands of the masseter muscle in children aged 3 to 8.

  Recruiting Aydin Adnan Menderes University · Aydin, Efeler · NCT07094581

• Using lacebacks during braces alignment

  This will see if using lacebacks on one side of the mouth helps patients aged 15 and older with fixed braces have better oral hygiene, fewer archwire problems, and different pain during the alignment phase.

  Recruiting International Islamic University Malaysia · Kuantan, Pahang · NCT07039071

• Patient experience with early versus delayed attachment placement during clear aligner treatment

  This trial tests whether delaying attachment placement until the third aligner reduces pain and improves quality of life for adults (18–40) receiving Biomax Nuvola clear aligners for malocclusion.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma · NCT06536335

• Assessing long-term dental effects of chemotherapy in childhood cancer survivors

  This study looks at the long-term dental health of childhood cancer survivors who had chemotherapy to see if they have more dental problems compared to kids who didn’t have cancer.

  Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Brussels · NCT06517927

• Evaluating how fixing crossbites affects children's speech

  This study tests if fixing crossbites in children aged 8 to 10 can improve their speech and overall quality of life.

  Recruiting Tanta University · Tanta, Gharbia Governorate · NCT06168695

• Comparing clear aligners and fixed braces for treating mild Class II malocclusion in adults

  This study is testing whether clear aligners or traditional braces work better for adults with mild Class II malocclusion to improve their teeth and bite.

  Recruiting Hama University · Hama, Hama Governorate · NCT05684510

• Improving orthodontic treatment with remote monitoring and AI

  This study is testing if using remote monitoring and AI can make orthodontic treatment with clear aligners more effective and convenient for patients by reducing office visits and improving their experience.

  Recruiting University of Illinois Chicago · Antioch, Illinois and 3 other locations · NCT05573308

• Impact of Malocclusions on Oral Health Quality of Life

  This study looks at how having crooked teeth affects the quality of life for teenagers aged 12-19 and sees if orthodontic treatment makes a difference compared to those who don’t get treatment.

  Recruiting at 2 sites Malmö University · Malmö, Skåne County and 2 other locations · NCT05038865

• Analyzing speech changes in jaw surgery patients

  This study looks at how jaw surgery affects the way people speak by recording their speech and tongue movements before and after the surgery.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT04117360

• Using a pacifier to fix dental issues in young children

  This study is testing if a special pacifier can help fix dental problems in young children who have been using pacifiers or bottles for a long time.

  Recruiting University Hospital, Basel, Switzerland · Basel · NCT03513003

Related topics

Quick answers

How many Malocclusion clinical trials are recruiting right now?

17, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (4 trials), Egypt (2 trials), Italy (2 trials), Yemen (1 trial), Syria (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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