Facially guided digital full-mouth rehabilitation
Facially Driven Digital Workflow for Esthetic and Functional Full-mouth Rehabilitation
This approach tries a fully digital, face-guided workflow to rebuild the mouths of adults (20–45) who have bite problems, missing lower molars, and are unhappy with their smile.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10 (estimated) |
| Ages | 20 Years to 45 Years |
| Sex | All |
| Sponsor | Menoufia University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Shibīn al Kawm, Menoufia) |
| Trial ID | NCT07314034 on ClinicalTrials.gov |
What this trial studies
This prospective observational project used a fully digital, facially driven workflow to plan and deliver complex full‑mouth rehabilitation. Teams created a 3D virtual patient by integrating intraoral scans, facial scans, and CBCT imaging to guide esthetic design, occlusion, and implant placement. Treatments included conservative lithium disilicate veneers, full‑coverage monolithic zirconia crowns, TAD‑assisted intrusion of extruded molars, and guided implant placement for missing mandibular molars. The integrated digital planning aimed to achieve precise restoration positioning, occlusal harmony, and predictable esthetic and functional outcomes with scheduled follow‑up.
Who should consider this trial
Good fit: Adults aged 20–45 with bite dysfunction or malocclusion, missing mandibular molars, adequate bone for implants or suitability for TAD‑assisted movement, and willingness to follow a fully digital workflow are ideal candidates.
Not a fit: Patients with uncontrolled systemic conditions, active oral infections or untreated periodontal disease, heavy smoking, recent head and neck radiation or bisphosphonate use, pregnancy, or inability to comply with treatment and follow‑up are unlikely to benefit.
Why it matters
Potential benefit: If successful, this approach could provide more precise implant placement, improved bite function, and a predictable esthetic restoration for eligible patients.
How similar studies have performed: Elements such as digital planning, guided implant placement, TAD‑assisted tooth movement, and ceramic restorations have documented success, but the fully integrated facially driven digital full‑mouth rehabilitation approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 20-45 years with partial or complete edentulism requiring full-mouth rehabilitation. * Patients with bite dysfunction, malocclusion, or esthetic concerns suitable for digital workflow treatment. * Adequate bone volume for implant placement or candidates for TAD-assisted tooth movement. * Willingness to undergo treatment using a fully digital, facially guided workflow and comply with follow-up visits. * Ability to provide informed consent. Exclusion Criteria: * Systemic conditions contraindicating implant or surgical procedures (e.g., uncontrolled diabetes, immunosuppression). * Active oral infections or untreated periodontal disease. * Heavy smokers (\>10 cigarettes/day) or substance abuse. * History of head and neck radiation therapy or bisphosphonate use. * Pregnancy or breastfeeding. * Inability to comply with treatment or follow-up protocol.
Where this trial is running
Shibīn al Kawm, Menoufia
- Faculty of Dentistry — Shibīn al Kawm, Menoufia, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohammed A. El-Sawy, PhD
- Email: Dr_sawy@windowslive.com
- Phone: 00201061314522
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.