Facially guided digital full-mouth rehabilitation
Official title: Facially Driven Digital Workflow for Esthetic and Functional Full-mouth Rehabilitation
Run by Menoufia University · NCT07314034 · Data updated 2026-11-12
This approach tries a fully digital, face-guided workflow to rebuild the mouths of adults (20–45) who have bite problems, missing lower molars, and are unhappy with their smile.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 45 Years |
| Sex | All |
| Enrollment | 10 (estimated) |
| Sponsor | Menoufia University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Shibīn al Kawm, Menoufia) |
| Status | Recruiting |
| Started | June 1, 2024 |
| Main results expected | September 1, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | January 2, 2026 |
| Trial ID | NCT07314034 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 20–45 with bite dysfunction or malocclusion, missing mandibular molars, adequate bone for implants or suitability for TAD‑assisted movement, and willingness to follow a fully digital workflow are ideal candidates.
✕Probably not a fit
Patients with uncontrolled systemic conditions, active oral infections or untreated periodontal disease, heavy smoking, recent head and neck radiation or bisphosphonate use, pregnancy, or inability to comply with treatment and follow‑up are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational project used a fully digital, facially driven workflow to plan and deliver complex full‑mouth rehabilitation. Teams created a 3D virtual patient by integrating intraoral scans, facial scans, and CBCT imaging to guide esthetic design, occlusion, and implant placement. Treatments included conservative lithium disilicate veneers, full‑coverage monolithic zirconia crowns, TAD‑assisted intrusion of extruded molars, and guided implant placement for missing mandibular molars. The integrated digital planning aimed to achieve precise restoration positioning, occlusal harmony, and predictable esthetic and functional outcomes with scheduled follow‑up.
Why it matters
Potential benefit: If successful, this approach could provide more precise implant placement, improved bite function, and a predictable esthetic restoration for eligible patients.
How similar studies have gone: Elements such as digital planning, guided implant placement, TAD‑assisted tooth movement, and ceramic restorations have documented success, but the fully integrated facially driven digital full‑mouth rehabilitation approach is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 20-45 years with partial or complete edentulism requiring full-mouth rehabilitation. * Patients with bite dysfunction, malocclusion, or esthetic concerns suitable for digital workflow treatment. * Adequate bone volume for implant placement or candidates for TAD-assisted tooth movement. * Willingness to undergo treatment using a fully digital, facially guided workflow and comply with follow-up visits. * Ability to provide informed consent. Exclusion Criteria: * Systemic conditions contraindicating implant or surgical procedures (e.g., uncontrolled diabetes, immunosuppression). * Active oral infections or untreated periodontal disease. * Heavy smokers (\>10 cigarettes/day) or substance abuse. * History of head and neck radiation therapy or bisphosphonate use. * Pregnancy or breastfeeding. * Inability to comply with treatment or follow-up protocol.
Where it's running
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Faculty of Dentistry
Shibīn al Kawm, Menoufia, Egypt Recruiting
Study contacts
- Study coordinator: Mohammed A. El-Sawy, PhD
- Email: Dr_sawy@windowslive.com
- Phone: 00201061314522
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.