Comparing clear aligners and fixed braces for treating mild Class II malocclusion in adults

Evaluation of Efficacy of Clear Aligners in Correction of Class II Malocclusion Using Intermaxillary Elastics: A Randomized Controlled

Not applicable Interventional Hama University · NCT05684510

This study is testing whether clear aligners or traditional braces work better for adults with mild Class II malocclusion to improve their teeth and bite.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages15 Years to 20 Years
SexAll
SponsorHama University Academic / other
Locations1 site (Hama, Hama Governorate)
Trial IDNCT05684510 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of clear aligners with intermaxillary elastics versus traditional fixed multibracket appliances in treating adult patients with mild Class II division 1 malocclusion and increased overjet. Participants will be divided into two groups: one receiving clear aligners and the other receiving fixed appliances. The study will assess changes in skeletal, dental, and soft tissue as a result of each treatment method. The goal is to determine which approach yields better outcomes for patients.

Who should consider this trial

Good fit: Ideal candidates are adults aged 15-20 with mild Class II division 1 malocclusion and moderate overjet.

Not a fit: Patients with periodontal disease, vertical growth patterns, or severe skeletal Class II malocclusion may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide patients with a more effective and comfortable treatment option for mild Class II malocclusion.

How similar studies have performed: Previous studies have shown promising results for clear aligners in orthodontic treatment, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* \- Patients with permanent occlusion at age 15-20 years.
* Patients with class II division I (half cusp or Less) with moderate overjet (2-4mm).
* Patients with normal or horizontal growth pattern.
* Mild crowding (\_\<2 mm) in maxillary and mandibular arch.
* Patient with satisfactory periodontal health and good oral hygiene
* No previous orthodontic treatment
* Comprehensive medical and dental history ruling out any systemic disease.

Exclusion Criteria:

* Patients with periodontal disease.
* Patients with vertical growth pattern.
* Patients with missing or extracted teeth except third molar.
* Patients with temporomandibular joint disorder.
* Patients with Skeletal open bite.
* Patients with poor oral and gingival health
* Patients with neuromuscular disorder.
* Patients with severe skeletal class II.

Where this trial is running

Hama, Hama Governorate

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions MalocclusionClass II Malocclusion
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.