Condition
Class II Malocclusion clinical trials and research
As of November 12, 2026, Find a Trial lists 6 Class II Malocclusion clinical trials that are recruiting, at sites in 4 countries (most in Egypt (3), Syria (1), Greece (1)). 1 was first registered in the last 30 days. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 1New in 30 days
- 4Countries
Newest Class II Malocclusion clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Maxillary Arch Distalization Using Infrazygomatic Crest Miniscrews for Class II Malocclusion | — | Al Mansurah, Dakahlia Governorate | Recruiting | Oct 15, 2026 |
| Custom-made versus ready-made Carriere Motion appliance for correcting Class II bite | — | Al Mansurah, Adakhlia | Recruiting | Jan 22, 2026 |
| 3D-printed fixed twin block versus MARA to help correct an underdeveloped lower jaw in Class II malocclusion | — | Al Mansurah, Dakahlia Governorate | Recruiting | Jan 14, 2026 |
| Distalizing upper first and second molars with a palate miniscrew device versus clear aligners | — | Thessaloniki | Recruiting | Jun 27, 2025 |
| Using Invisalign with special blocks for jaw advancement | — | Richmond, British Columbia and 2 other locations | Recruiting | Oct 22, 2024 |
| Comparing clear aligners and fixed braces for treating mild Class II malocclusion in adults | — | Hama, Hama Governorate | Recruiting | Jan 13, 2023 |
All recruiting trials (6)
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Maxillary Arch Distalization Using Infrazygomatic Crest Miniscrews for Class II Malocclusion
This study tests if moving the upper dental arch backward with infrazygomatic crest miniscrews safely corrects Class II malocclusion without extra patient cooperation.
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Custom-made versus ready-made Carriere Motion appliance for correcting Class II bite
This study will test whether a custom-made Carriere Motion appliance works better than a ready-made version to correct Class II malocclusion in 12–15-year-olds with permanent teeth.
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3D-printed fixed twin block versus MARA to help correct an underdeveloped lower jaw in Class II malocclusion
This research will test whether a CAD/CAM 3D-printed fixed twin block or a MARA appliance better improves dental alignment and jaw relationships in preadolescents with Class II due to a small lower jaw.
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Distalizing upper first and second molars with a palate miniscrew device versus clear aligners
This trial will test whether a miniscrew‑supported palate device (AMDA®) or clear aligners with Class II elastics moves upper first and second molars back more effectively in people with bilateral Class II malocclusion who need molar distalization.
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Using Invisalign with special blocks for jaw advancement
This study tests if using special blocks with Invisalign can help people with jaw alignment issues feel more comfortable and improve their dental health.
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Comparing clear aligners and fixed braces for treating mild Class II malocclusion in adults
This study is testing whether clear aligners or traditional braces work better for adults with mild Class II malocclusion to improve their teeth and bite.
Related topics
Quick answers
How many Class II Malocclusion clinical trials are recruiting right now?
6, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in Egypt (3 trials), Syria (1 trial), Greece (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.