Condition

Lewy Body Disease clinical trials and research

• 16Clinical trials
• 11NIH research projects
• 12Countries

Newest Lewy Body Disease clinical trials

All recruiting trials (16)

• A look at why Lewy body conditions cause visual hallucinations

  This study tests brain‑imaging in people with Lewy body diseases who do or don’t experience visual hallucinations, and in healthy volunteers, to see how brain networks might create these images.

  Recruiting NYU Langone Health · New York, New York · NCT07849413

• Donanemab in Early Cognitive Decline with Lewy Body Features (TRAILBLAZER-ALZ 7)

  This trial tests donanemab versus placebo to see if it can slow thinking and daily-function decline in people with early cognitive decline and Lewy body disease features.

  Recruiting at 47 sites Phase 2 Eli Lilly and Company · Chandler, Arizona and 71 other locations · NCT07589595

• Hyperspectral retinal imaging to detect Alzheimer’s and other neurodegenerative changes

  This project will test whether a special retinal camera that scans many wavelengths of light can detect signs of Alzheimer’s and other neurodegenerative diseases in people with dementia or at risk.

  Recruiting Center for Eye Research Australia · Melbourne, Victoria · NCT07545473

• Swedish BioFINDER Sleep program for early Parkinson's disease and REM sleep behavior disorder

  This project will test whether sleep studies, brain and heart imaging, and fluid biomarkers can identify synuclein pathology and help predict progression in people with early Parkinson's disease or idiopathic REM sleep behavior disorder.

  Recruiting Skane University Hospital · Malmö · NCT07533799

• Linking EEG brain activity and pathology in Lewy body disease

  This project will test whether distinct EEG activity patterns can help identify and explain Lewy body disease in adults who had prior EEGs and RT-QuIC testing.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07335692

• Using brain stimulation and digital training to improve cognitive function in older adults

  This study is testing whether a combination of brain stimulation and digital training can help improve thinking skills in older adults with Mild Cognitive Impairment and Alzheimer's Disease.

  Recruiting Universidade Federal do Rio de Janeiro · Rio de Janeiro, Rio de Janeiro · NCT06733714

• Collecting data on neurodegenerative diseases progression markers

  This study is trying to find new signs that can help doctors understand how neurodegenerative diseases like Parkinson's progress, so they can improve early treatment options for patients.

  Recruiting IRCCS San Raffaele Roma · Cassino, Frosinone · NCT06596746

• Biobank for studying ALS and Alzheimer's diseases

  This study is collecting blood, skin samples, and health information from people to see how genetics might help us understand and find treatments for ALS and Alzheimer's disease.

  Recruiting New York Stem Cell Foundation Research Institute · New York, New York · NCT06203106

• Investigating new blood tests for diagnosing memory disorders

  This study is testing new blood tests to see if they can help diagnose memory disorders like mild dementia and Alzheimer's better than the current method that uses spinal fluid.

  Recruiting Skane University Hospital · Malmö · NCT06122415

• Improving early diagnosis of dementia in primary care

  This study is trying to find better ways to diagnose Alzheimer's and other memory problems early in people visiting their primary care doctors.

  Recruiting Skane University Hospital · Malmö · NCT06120361

• Investigating brain changes in Lewy Body Disease and Alzheimer's Disease

  This study looks at how brain function, memory, and movement are affected in people with Lewy Body Disease and Alzheimer's, compared to healthy individuals, using brain scans and other tests.

  Recruiting Mayo Clinic · Scottsdale, Arizona · NCT06057909

• Improving language comprehension in Lewy body disease using brain stimulation

  This study is testing if a type of brain stimulation can help improve language skills in older adults with Lewy body disease and mild cognitive impairment.

  Recruiting Masaryk University · Brno · NCT05847985

• Optimizing PET Imaging with 18F-DOPA for Various Conditions

  This study is testing if a special imaging technique using 18F-DOPA can help doctors see and understand conditions like congenital hyperinsulinism, neuroblastoma, neuroendocrine tumors, Parkinson's disease, and Lewy body dementia better in both kids and adults.

  Recruiting Phase 3 University of Alberta · Edmonton, Alberta · NCT04706910

• Using advanced eye imaging to study memory impairment

  This study is trying to see if new eye imaging techniques can help find changes in the retina that might be linked to memory problems like Alzheimer's and other types of dementia.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT04389437

• A study on early diagnosis and biomarkers for dementia and related diseases

  This study is testing new ways to spot dementia and related diseases early by looking for specific markers in the brain and body, to help people at high risk and track how well new treatments are working.

  Recruiting at 2 sites Skane University Hospital · Ängelholm and 1 other locations · NCT03174938

• Treatment for neurologic disorders using stem cells

  This study is testing whether using stem cells from patients' own bone marrow can help improve brain and nerve function in people with serious neurologic disorders that don't respond well to regular treatments.

  Recruiting at 3 sites MD Stem Cells · Westport, Connecticut and 2 other locations · NCT02795052

NIH-funded research (11)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Gut-immune changes in Lewy Body Diseases and early signs

  A study at Stanford will explore how the gut and its immune system may be linked to Lewy Body diseases like Parkinson’s and related conditions, with findings that could point to new ways to understand and someday treat these illnesses.

  NIH research Stanford University · Stanford, United States · NIH-11596965

• Gut-immune system links in Lewy Body Disease

  Researchers are studying how the gut and immune system may influence Lewy body diseases like Parkinson’s and dementia with Lewy bodies, aiming to uncover new clues that could lead to better diagnosis and treatment in the future.

  NIH research Stanford University · Stanford, United States · NIH-11372296

• Amygdala’s role in Lewy body disease and Alzheimer’s disease

  A clinician-science training grant to help Dr. D. Luke Fischer study how the amygdala may drive the spread of disease in people with Lewy body disease and Alzheimer’s disease.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11371857

• Gut immune changes in Lewy body disorders

  This project looks at whether changes in gut immune signals and gut bacteria are linked to Parkinson's disease, dementia with Lewy bodies, and people with early signs like REM sleep behavior disorder.

  NIH research Stanford University · Stanford, United States · NIH-11369405

• Automated Neurodegeneration Index for Lewy Body Disease in At-Risk Groups

  A new machine‑learning tool analyzes routine brain scans to identify early neurodegeneration in people at risk for Parkinson’s disease or dementia with Lewy bodies.

  NIH research University of Florida · Gainesville, United States · NIH-11342086

• Identifying molecules that interact with alpha-synuclein in Alzheimer's disease–related dementias

  A study at Mayo Clinic Jacksonville will map which proteins interact with alpha-synuclein in brain tissue and human-derived cells to understand its role in dementia like Lewy body disease and Alzheimer’s-related dementias.

  NIH research Mayo Clinic Jacksonville · Jacksonville, United States · NIH-11319079

• Restoring the brain's cleanup cells to help in Lewy body disease

  This project looks at whether removing and then regrowing the brain's immune cells can help clear harmful protein clumps that damage people with Lewy body disease.

  NIH research Duquesne University · Pittsburgh, United States · NIH-11194408

• Gut Immunity and Lewy Body Disease

  This research explores how changes in the gut's immune system might be connected to conditions like Parkinson's disease and dementia with Lewy bodies.

  NIH research Stanford University · Stanford, United States · NIH-11172495

• Investigating how to restore immune cells in the brain affected by Lewy body disease

  This study is looking at how a protein linked to Lewy body disorders affects the brain, especially in areas that control smell and memory, and it’s testing a new oral medication that might help boost the brain's immune system to clear out these harmful proteins and improve brain health.

  NIH research Duquesne University · Pittsburgh, United States · NIH-11038250

• Investigating the gut's immune response in Lewy Body Disease

  This study is looking at how the bacteria in our gut and our immune system might be linked to conditions like Parkinson's Disease and Lewy body dementia, with the hope of finding new ways to help people with these diseases.

  NIH research Stanford University · Stanford, United States · NIH-10988065

• Investigating protein aggregation in Lewy Body Disease using zebrafish models

  This study is looking at how a protein called alpha-synuclein clumps together in brain cells and affects communication between them, using zebrafish to help understand this process better, which could eventually lead to new treatments for Lewy Body Disease and similar conditions.

  NIH research Lewis and Clark College · Portland, United States · NIH-10731005

Related topics

Quick answers

How many Lewy Body Disease clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (5 trials), Sweden (4 trials), France (2 trials), Japan (1 trial), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →