Investigating new blood tests for diagnosing memory disorders
The Swedish BioFINDER - Memory Clinic Study
This study is testing new blood tests to see if they can help diagnose memory disorders like mild dementia and Alzheimer's better than the current method that uses spinal fluid.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Sex | All |
| Sponsor | Skane University Hospital Academic / other |
| Locations | 1 site (Malmö) |
| Trial ID | NCT06122415 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of newly developed blood biomarkers for diagnosing memory-related conditions such as mild dementia and Alzheimer's disease. Conducted at the Memory Clinic of Skåne University Hospital in Malmö, it will involve 1200 patients who will provide blood and cerebrospinal fluid samples. The study will compare the diagnostic accuracy of blood tests against traditional cerebrospinal fluid tests to determine if blood tests can serve as a more cost-effective and patient-friendly alternative. The results will be assessed in a three-step process by the attending physician to gauge the impact on clinical decision-making.
Who should consider this trial
Good fit: Ideal candidates are individuals undergoing clinical evaluations for cognitive symptoms at the Memory Clinic who are scheduled for cerebrospinal fluid and blood sampling.
Not a fit: Patients who are not undergoing cerebrospinal fluid or blood sampling as part of their clinical practice will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and accessible diagnostic methods for patients with memory disorders.
How similar studies have performed: Other studies have shown promise in using blood biomarkers for diagnosing Alzheimer's disease, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Under investigation for cognitive symptoms at the Memory clinic. 2. Cerebrospinal fluid and blood sampling is planned to be done as part of clinical practice even if the patient is not taking part of this study. Exclusion Criteria: 1. Not undergoing CSF or blood sampling as part of clinical practice. 2. Not undergoing cognitive testing as part of clinical practice.
Where this trial is running
Malmö
- Skåne University Hospital — Malmö, Sweden (Recruiting)
Study contacts
- Principal investigator: Erik Stomrud, MD, PhD — Skane University Hospital and Lund University
- Study coordinator: Erik Stomrud, MD, PhD
- Email: erik.stomrud@med.lu.se
- Phone: +46 40 33 10 00
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.