Improving language comprehension in Lewy body disease using brain stimulation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of transcranial direct current stimulation (tDCS) on language comprehension in patients with Lewy body diseases (LBDs) who also have mild cognitive impairment (MCI). The research focuses on understanding how non-invasive brain stimulation can address language dysfunctions that are often overlooked in LBD patients. By targeting the cognitive aspects of LBDs, the study aims to enhance social and occupational functioning, thereby improving the quality of life for affected individuals. Participants will be right-handed Czech speakers aged 60-80 with specific inclusion criteria related to their cognitive status.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* right-handedness
* Czech as their first language
* age (60-80 years)
* presence of PD-MCI (Litvan et al. 2012) or MCI-LB (McKeith et al. 2020) for LBD subjects

Exclusion Criteria:

* cardio pacemaker
* any MRI-incompatible metal in the body
* epilepsy
* any diagnosed psychiatric disorders
* alcohol/drug abuse
* for HC group the presence of LBDs or other neurodegenerative disorder or MCI/dementia

Where it's running

• Masaryk University CEITEC
  Brno, Czechia Recruiting

Study contacts

• Study coordinator: Lubomira Novakova
• Email: lubomira.novakova@ceitec.muni.cz
• Phone: +420 549 497 766

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.