Investigating the gut's immune response in Lewy Body Disease
Role of altered gut immune response in Lewy Body Disease
This study is looking at how the bacteria in our gut and our immune system might be linked to conditions like Parkinson's Disease and Lewy body dementia, with the hope of finding new ways to help people with these diseases.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10988065 on NIH RePORTER |
What this research studies
This research explores the connection between the gut microbiota and immune system in patients with Lewy Body Diseases, such as Parkinson's Disease and dementia with Lewy bodies. It aims to understand how changes in the gut and immune responses may contribute to the progression of these neurological disorders. By utilizing advanced technologies, the study will analyze various biological parameters in patients, including those with early signs of Lewy Body Disease. The goal is to uncover potential pathways that could lead to new treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Lewy Body Diseases or those showing early signs, such as isolated REM Sleep Behavior Disorder.
Not a fit: Patients with Lewy Body Diseases who do not have any gastrointestinal symptoms or immune system involvement may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and therapies that improve the management of Lewy Body Diseases.
How similar studies have performed: While the interplay between gut health and neurological diseases is an emerging field, this specific approach is relatively novel and has not been extensively tested in the context of Lewy Body Diseases.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Poston, Kathleen Lombard — Stanford University
- Study coordinator: Poston, Kathleen Lombard
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.