Condition

Kaposi Sarcoma clinical trials and research

• 12Clinical trials
• 29NIH research projects
• 8Countries

Newest Kaposi Sarcoma clinical trials

All recruiting trials (12)

• CYT107 (recombinant interleukin-7) to treat Kaposi sarcoma in adults with HIV and poor T‑cell recovery

  This trial tests whether CYT107, a laboratory-made interleukin-7, can shrink Kaposi sarcoma tumors in adults with HIV who have poor T‑cell recovery.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07308886

• Using AI to improve monitoring of Kaposi Sarcoma

  This study is testing a new low-cost device that uses AI to help doctors better track and measure Kaposi Sarcoma in patients with darker skin in Uganda and Kenya.

  Recruiting Washington University School of Medicine · Kisumu and 1 other locations · NCT06898203

• Using advanced imaging to evaluate Kaposi sarcoma

  This study is testing if a special 3D camera can help doctors get better images of Kaposi sarcoma skin lesions in patients to track how well treatments are working.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT06751355

• Propranolol for treating Kaposi sarcoma in adults

  This trial will test whether the oral beta‑blocker propranolol can shrink Kaposi sarcoma lesions in adults, including people living with HIV.

  Recruiting Phase 2 Washington University School of Medicine · St Louis, Missouri · NCT06445166

• Understanding the natural history of Kaposi Sarcoma

  This study looks at how Kaposi Sarcoma affects people with weakened immune systems, like those with HIV, by tracking their symptoms and health over time.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06375122

• Peer support program to improve cancer diagnosis and treatment for young people with HIV in Zambia

  This study is testing a peer support program to help young people with HIV in Zambia get diagnosed and treated for cancer more effectively.

  Recruiting Implenomics · Lusaka · NCT06004011

• MQ710 with or without pembrolizumab for advanced skin and other solid tumors

  This will test different doses of MQ710, alone or together with pembrolizumab, in adults with advanced or recurrent solid tumors (including skin cancers) to find a safe dose with mild side effects.

  Recruiting at 5 sites Phase 1 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT05859074

• Propranolol for Kaposi Sarcoma

  This study tests whether propranolol can help treat Kaposi sarcoma in children and adults.

  Recruiting Phase 2 AIDS Malignancy Consortium · Buenos Aires and 5 other locations · NCT05797662

• Collecting blood and tissue samples for HIV/AIDS-related cancer research

  This study is collecting blood and tissue samples from people living with HIV and related cancers to help researchers learn more about how HIV affects cancer development.

  Recruiting at 8 sites AIDS Malignancy Consortium · La Jolla, California and 7 other locations · NCT05663502

• Using abemaciclib to treat Kaposi Sarcoma in patients with and without HIV

  This study is testing if a new medication called abemaciclib can safely help shrink Kaposi Sarcoma tumors in both HIV-positive and HIV-negative patients.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04941274

• Combination of pomalidomide and nivolumab for treating virus-related cancers

  This study is testing a new combination of two medications, pomalidomide and nivolumab, to see if it can help adults with certain virus-related cancers that haven't improved with other treatments.

  Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04902443

• Treatment for advanced Kaposi Sarcoma using NHS-IL12 and M7824

  This study is testing if a new treatment using NHS-IL12 alone or with M7824 can help people with advanced Kaposi Sarcoma, especially those with weakened immune systems like those living with HIV.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04303117

NIH-funded research (29)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Precision 3D Imaging to Monitor Kaposi Sarcoma (KS) with SkinScan3D

  A new portable 3D imaging tool called SkinScan3D will help doctors measure KS skin lesions more accurately and quickly, especially in people living with HIV.

  NIH research Washington University · Saint Louis, United States · NIH-11535366

• Precision 3D Imaging to Track Kaposi Sarcoma (KS) with SkinScan3D

  A new 3D imaging tool called SkinScan3D helps doctors monitor Kaposi sarcoma lesions more accurately and quickly, especially in settings with high KS burden like East Africa and in U.S. clinics with HIV patients.

  NIH research Washington University · Saint Louis, United States · NIH-11535365

• Kaposi Sarcoma care and research in Africa during ART era

  A collaborative program to better understand and improve diagnosis, treatment, and prevention of Kaposi sarcoma for people living with HIV in Zambia and Tanzania.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11535231

• Kaposi Sarcoma in Africa: ART Era Research Network

  A collaborative program in Africa and the United States will study Kaposi sarcoma in people living with HIV on ART to improve diagnosis, treatment, and prevention.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11535230

• Kaposi Sarcoma in Africa in the ART Era

  This grant supports research to improve how Kaposi sarcoma is detected, treated, and understood in people living with HIV in Zambia and Tanzania during ART, with collaboration between African hospitals and a U.S. center.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11417959

• Faster detection and connection to care for people with HIV who develop Kaposi sarcoma in East Africa

  This project aims to speed up finding people with HIV diagnosed with Kaposi sarcoma in East Africa and help them get linked to care more quickly.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11416376

• Rapid case finding to connect people with HIV and Kaposi sarcoma to care in East Africa

  This project works to find people with HIV who develop Kaposi sarcoma more quickly and help them get into medical care sooner.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11416317

• Faster diagnosis and care for HIV-related Kaposi sarcoma in East Africa

  This project helps identify people with HIV who develop Kaposi sarcoma in East Africa and connects them quickly to medical care.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11416275

• Kaposi sarcoma care and research in Zambia and Tanzania

  Researchers are working with hospitals in Zambia and Tanzania to improve how Kaposi sarcoma is found, treated, and understood for people living with HIV on antiretroviral therapy.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11412992

• Kaposi sarcoma care and research partnership in Zambia and Tanzania

  This program connects hospitals in Zambia, Tanzania, and the U.S. to improve how Kaposi sarcoma is found, treated, and understood in people living with HIV on antiretroviral therapy.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11412991

• Defining Key Vulnerable Targets to Prevent KSHV-Related Diseases

  Aiming to map the parts of the Kaposi sarcoma-associated herpesvirus (KSHV) that antibodies should target to block infection and disease, with samples from people living with HIV.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11411253

• Precision 3D imaging to monitor Kaposi sarcoma (KS) with SkinScan3D

  A new portable 3D imaging tool uses AI to measure KS skin lesions more quickly and objectively, helping people withKS and their clinicians track treatment.

  NIH research Washington University · Saint Louis, United States · NIH-11402685

• 3D skin imaging for Kaposi sarcoma care

  This project will use a portable 3D imaging device with AI to measure Kaposi sarcoma skin lesions more accurately for people receiving treatment in East Africa.

  NIH research Washington University · Saint Louis, United States · NIH-11400582

• Precision 3D imaging to improve Kaposi sarcoma care

  A portable 3D camera with built-in AI will be used to measure Kaposi sarcoma skin lesions more precisely for people getting KS care in East Africa.

  NIH research Washington University · Saint Louis, United States · NIH-11400231

• Targeted therapies for HIV-related Kaposi sarcoma and lymphoma

  A patient-focused look at new targets and drug combinations to treat Kaposi sarcoma and AIDS-related lymphomas in people living with HIV.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11357655

• Improving care and understanding of Kaposi sarcoma in Zambia and Tanzania

  Researchers are partnering with hospitals in Zambia, Tanzania, and the United States to improve diagnosis, treatment, and prevention of Kaposi sarcoma for people living with HIV.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11184252

• Pinpointing weak spots in the Kaposi sarcoma herpesvirus to help create a vaccine

  Researchers will map where protective antibodies attach to the Kaposi sarcoma–associated herpesvirus and test whether those antibodies can block infection, aiming to help people at risk for Kaposi sarcoma, especially people living with HIV.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11164636

• 3D skin imaging for Kaposi sarcoma

  This project will use a portable 3D camera with AI to measure Kaposi sarcoma skin lesions more precisely for patients in East Africa.

  NIH research Washington University · Saint Louis, United States · NIH-11163458

• New treatments for Kaposi sarcoma and lymphoma in people with HIV

  This project looks for new ways to treat Kaposi sarcoma and lymphoma, common cancers in people living with HIV.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11124104

• Faster diagnosis and quicker cancer care for people with Kaposi sarcoma in East Africa

  This project rapidly finds adults newly diagnosed with Kaposi sarcoma in East Africa and helps them get linked to HIV and cancer care.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11112403

• Understanding Kaposi Sarcoma in HIV Patients in Africa

  This study is all about improving how we find and treat Kaposi sarcoma, a type of cancer linked to HIV/AIDS, in Zambia and Tanzania, by bringing together hospitals and researchers to better understand the disease and help patients get the care they need.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11090175

• Identifying key immune responses to develop a vaccine for Kaposi sarcoma-associated herpesvirus.

  This study is looking at how the immune system reacts to a virus linked to certain cancers, especially in people with HIV, to help develop a vaccine that could protect against it.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11003468

• Improving the monitoring of Kaposi sarcoma treatment using advanced imaging technology.

  This study is testing a new tool called SkinScan3D to help doctors better track how well treatments are working for people with Kaposi sarcoma, especially in places where healthcare can be challenging, so patients can get the best care possible.

  NIH research Washington University · Saint Louis, United States · NIH-10951388

• Understanding Kaposi Sarcoma in HIV Patients in Africa

  This study is working to improve how Kaposi sarcoma, a cancer often linked to HIV/AIDS, is diagnosed and treated in Zambia and Tanzania by bringing together different health organizations to better understand the disease and support patients.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-10908991

• Investigating how a viral gene contributes to Kaposi's sarcoma development

  This study is looking at how a certain viral gene might help cause Kaposi's sarcoma, a type of cancer that can happen with AIDS, and it's using special animal models to find out more about how this gene affects tumor growth, which could lead to better treatments for people with this condition.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-10892646

• Understanding how HIV-related Kaposi Sarcoma progresses in patients receiving local treatment in Malawi and South Africa

  This study is looking at how different factors affect the growth of Kaposi Sarcoma in people with HIV in Malawi and South Africa, with the goal of finding better treatments and ways to predict how the disease will progress.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10891545

• New ways to screen and predict outcomes for HIV-related cancers in Malawi and South Africa

  This study is working to find better ways to detect and understand cancers linked to HIV, like Kaposi sarcoma, cervical cancer, and lymphoma, in Malawi and South Africa, so that people living with HIV can get the help they need more effectively.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10891536

• Improving diagnosis and care for HIV-infected patients with Kaposi Sarcoma in East Africa

  This study is working to improve how we find and treat Kaposi Sarcoma in people with HIV in East Africa, helping them get the care they need more quickly and understand what makes the disease worse, all while partnering with local healthcare providers in Uganda and Kenya.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10866372

• Creating a mouse model to study Kaposi Sarcoma

  This study is creating special mice to help us learn more about Kaposi Sarcoma, a cancer that affects people with HIV/AIDS, so we can better understand how it develops and find new treatments that might help patients.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10783749

Related topics

Quick answers

How many Kaposi Sarcoma clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (9 trials), Uganda (2 trials), Kenya (1 trial), Argentina (1 trial), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1/2: 2, Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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