NIH-funded research NIH-funded research

Kaposi sarcoma care and research in Zambia and Tanzania

Official title: Kaposi Sarcoma in the Era of ART in Africa Program (KEAAP)

Funded at Lsu Health Sciences Center · NIH-11412992 · Data updated 2026-11-12

Researchers are working with hospitals in Zambia and Tanzania to improve how Kaposi sarcoma is found, treated, and understood for people living with HIV on antiretroviral therapy.

More Sarcoma research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLsu Health Sciences Center
NIH-funded
Lab location1 site (New Orleans, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2025
Award (this year)$282,153
NIH project number3U54CA277846-03S2
Project IDNIH-11412992 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are people living with HIV in Zambia or Tanzania, especially those diagnosed with or at risk for Kaposi sarcoma who receive care at the partner hospitals.

Less likely to help

People without HIV, patients with cancers unrelated to Kaposi sarcoma, or individuals living outside the participating regions are unlikely to benefit directly from this program.

What this research studies

If you take part, you would be connected with cancer centers in Zambia or Tanzania that are studying Kaposi sarcoma in people on HIV treatment. Teams will collect clinical information and tissue samples, improve diagnosis and treatment steps, and study how the virus and immune system affect KS. The program also trains local clinicians and builds lab and research capacity so care and follow-up can get better where you live. The combined clinical and lab work aims to reduce KS cases and improve outcomes for patients in sub-Saharan Africa.

Why it matters

Potential benefit: If successful, this work could lead to earlier detection, better treatment, and stronger prevention of Kaposi sarcoma for people living with HIV in the region.

How similar studies have gone: Regional clinical and translational efforts have improved care for HIV-associated cancers before, but this coordinated multi-country program focused on KS across detection, care, and biology is relatively new.

Where this research is happening

  • Lsu Health Sciences Center
    New Orleans, United States
    Active

Researchers

  • Principal investigator: Wood, Charles — Lsu Health Sciences Center
  • Study coordinator: Wood, Charles

Related research

Other NIH-funded projects on the same topics.

  • Precision 3D Imaging to Monitor Kaposi Sarcoma (KS) with SkinScan3D

    A new portable 3D imaging tool called SkinScan3D will help doctors measure KS skin lesions more accurately and quickly, especially in people living with HIV.

    NIH research Washington University · Saint Louis, United States · NIH-11535366

  • Precision 3D Imaging to Track Kaposi Sarcoma (KS) with SkinScan3D

    A new 3D imaging tool called SkinScan3D helps doctors monitor Kaposi sarcoma lesions more accurately and quickly, especially in settings with high KS burden like East Africa and in U.S. clinics with HIV patients.

    NIH research Washington University · Saint Louis, United States · NIH-11535365

  • Kaposi Sarcoma care and research in Africa during ART era

    A collaborative program to better understand and improve diagnosis, treatment, and prevention of Kaposi sarcoma for people living with HIV in Zambia and Tanzania.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11535231

  • Kaposi Sarcoma in Africa: ART Era Research Network

    A collaborative program in Africa and the United States will study Kaposi sarcoma in people living with HIV on ART to improve diagnosis, treatment, and prevention.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11535230

  • Kaposi Sarcoma in Africa in the ART Era

    This grant supports research to improve how Kaposi sarcoma is detected, treated, and understood in people living with HIV in Zambia and Tanzania during ART, with collaboration between African hospitals and a U.S. center.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11417959

  • Faster detection and connection to care for people with HIV who develop Kaposi sarcoma in East Africa

    This project aims to speed up finding people with HIV diagnosed with Kaposi sarcoma in East Africa and help them get linked to care more quickly.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11416376

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.