Kaposi Sarcoma in Africa in the ART Era
Official title: Kaposi Sarcoma in the Era of ART in Africa Program (KEAAP)
Funded at Lsu Health Sciences Center · NIH-11417959 · Data updated 2026-11-12
This grant supports research to improve how Kaposi sarcoma is detected, treated, and understood in people living with HIV in Zambia and Tanzania during ART, with collaboration between African hospitals and a U.S. center.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lsu Health Sciences Center NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $364,238 |
| NIH project number | 5U54CA277846-04 |
| Project ID | NIH-11417959 on NIH RePORTER |
Who could benefit from this research
✓Could help
HIV-positive adults in Zambia and Tanzania diagnosed with or at risk for Kaposi sarcoma, and patients treated at collaborating centers who consent to participation and sample collection.
✕Less likely to help
Patients without KS or not receiving care at partner sites may not directly benefit from this project.
What this research studies
Kaposi sarcoma remains a common HIV-associated cancer even with ART, and KEAAP creates a collaborative network to study KS from detection to treatment and biology. The project will build three core facilities, fund two KS research projects led by experienced researchers, and train future investigators in both Africa and the United States. Through in-country clinics and shared specimens, researchers will examine disease progression, immune responses, and viral reservoirs to inform better care. The consortium emphasizes capacity building, long-term partnerships, and sustainable research infrastructure in LMIC settings. Participants would be drawn from HIV-positive populations treated at partnering hospitals in Zambia and Tanzania, with data and samples collected under ethical approvals.
Why it matters
Potential benefit: Improved diagnosis, staging, and management of KS in HIV-positive patients in Africa, potentially leading to better outcomes and long-term research capacity.
How similar studies have gone: The program builds on prior U.S.–Africa collaborations and aims to expand successful models of KS research and capability building in LMIC settings.
Where this research is happening
-
Lsu Health Sciences Center
New Orleans, United States Active
Researchers
- Principal investigator: Wood, Charles — Lsu Health Sciences Center
- Study coordinator: Wood, Charles
Related research
Other NIH-funded projects on the same topics.
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Precision 3D Imaging to Monitor Kaposi Sarcoma (KS) with SkinScan3D
A new portable 3D imaging tool called SkinScan3D will help doctors measure KS skin lesions more accurately and quickly, especially in people living with HIV.
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Precision 3D Imaging to Track Kaposi Sarcoma (KS) with SkinScan3D
A new 3D imaging tool called SkinScan3D helps doctors monitor Kaposi sarcoma lesions more accurately and quickly, especially in settings with high KS burden like East Africa and in U.S. clinics with HIV patients.
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Kaposi Sarcoma care and research in Africa during ART era
A collaborative program to better understand and improve diagnosis, treatment, and prevention of Kaposi sarcoma for people living with HIV in Zambia and Tanzania.
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Kaposi Sarcoma in Africa: ART Era Research Network
A collaborative program in Africa and the United States will study Kaposi sarcoma in people living with HIV on ART to improve diagnosis, treatment, and prevention.
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Faster detection and connection to care for people with HIV who develop Kaposi sarcoma in East Africa
This project aims to speed up finding people with HIV diagnosed with Kaposi sarcoma in East Africa and help them get linked to care more quickly.
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Rapid case finding to connect people with HIV and Kaposi sarcoma to care in East Africa
This project works to find people with HIV who develop Kaposi sarcoma more quickly and help them get into medical care sooner.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.