NIH-funded research U01 cooperative agreement

Precision 3D imaging to improve Kaposi sarcoma care

Official title: PRecision IMaging to Evaluate Kaposi Sarcoma (PRIME-KS)

Funded at Washington University · NIH-11400231 · Data updated 2026-11-12

A portable 3D camera with built-in AI will be used to measure Kaposi sarcoma skin lesions more precisely for people getting KS care in East Africa.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionWashington University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startAugust 7, 2024
Project endJuly 31, 2029
Funding year2025
Award (this year)$122,208
NIH project number3U01CA292765-02S1
Project IDNIH-11400231 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are people with visible Kaposi sarcoma skin lesions who receive care at participating clinics in East Africa (for example, sites in Malawi, Mozambique, Uganda, or Kenya).

Less likely to help

People with only internal (visceral) Kaposi sarcoma, those not treated at participating clinics, or anyone unable to attend imaging visits would likely not benefit directly from this effort.

What this research studies

You would have your skin lesions photographed with a small portable 3D imaging device (SkinScan3D) that captures lesion height, area, and volume. The device combines liquid-lens optics and AI to turn images into objective size measurements rather than relying only on visual checks. Researchers will work directly with clinicians, nurses, and patients at clinics in East Africa to refine how the device is used and fit it into normal clinic visits. The aim is to make tracking response to therapy faster, less subjective, and more practical in busy clinics.

Why it matters

Potential benefit: If successful, this could give your care team more accurate, objective measurements so treatment can be tailored and unnecessary chemotherapy exposure reduced.

How similar studies have gone: Some prior digital-photo and AI efforts have helped track skin lesions, but combining portable high-resolution 3D imaging with AI for Kaposi sarcoma is largely novel and still being tested.

Where this research is happening

  • Washington University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Odeny, Thomas — Washington University
  • Study coordinator: Odeny, Thomas

Related research

Other NIH-funded projects on the same topics.

  • Precision 3D Imaging to Monitor Kaposi Sarcoma (KS) with SkinScan3D

    A new portable 3D imaging tool called SkinScan3D will help doctors measure KS skin lesions more accurately and quickly, especially in people living with HIV.

    NIH research Washington University · Saint Louis, United States · NIH-11535366

  • Precision 3D Imaging to Track Kaposi Sarcoma (KS) with SkinScan3D

    A new 3D imaging tool called SkinScan3D helps doctors monitor Kaposi sarcoma lesions more accurately and quickly, especially in settings with high KS burden like East Africa and in U.S. clinics with HIV patients.

    NIH research Washington University · Saint Louis, United States · NIH-11535365

  • Kaposi Sarcoma care and research in Africa during ART era

    A collaborative program to better understand and improve diagnosis, treatment, and prevention of Kaposi sarcoma for people living with HIV in Zambia and Tanzania.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11535231

  • Kaposi Sarcoma in Africa: ART Era Research Network

    A collaborative program in Africa and the United States will study Kaposi sarcoma in people living with HIV on ART to improve diagnosis, treatment, and prevention.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11535230

  • Kaposi Sarcoma in Africa in the ART Era

    This grant supports research to improve how Kaposi sarcoma is detected, treated, and understood in people living with HIV in Zambia and Tanzania during ART, with collaboration between African hospitals and a U.S. center.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11417959

  • Faster detection and connection to care for people with HIV who develop Kaposi sarcoma in East Africa

    This project aims to speed up finding people with HIV diagnosed with Kaposi sarcoma in East Africa and help them get linked to care more quickly.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11416376

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.