NIH-funded research U01 cooperative agreement

3D skin imaging for Kaposi sarcoma

Official title: PRecision IMaging to Evaluate Kaposi Sarcoma (PRIME-KS)

Funded at Washington University · NIH-11163458 · Data updated 2026-11-12

This project will use a portable 3D camera with AI to measure Kaposi sarcoma skin lesions more precisely for patients in East Africa.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionWashington University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startAugust 7, 2024
Project endJuly 31, 2029
Funding year2025
Award (this year)$321,333
NIH project number5U01CA292765-02
Project IDNIH-11163458 on NIH RePORTER

Who could benefit from this research

Could help

People with visible cutaneous Kaposi sarcoma lesions who receive care at participating clinics in East Africa and are willing to have lesion images taken are ideal candidates.

Less likely to help

Patients with only internal (visceral) Kaposi sarcoma, those unable to reach participating clinics, or those not receiving skin-directed monitoring may not directly benefit.

What this research studies

You would have your Kaposi sarcoma skin lesions photographed with a handheld device called SkinScan3D that creates high-resolution 3D images showing lesion height and volume. Nurses and clinicians will help refine how the device is used during routine visits so it fits into busy clinics. The images and AI-generated measurements will be used to track response to treatment and reduce reliance on slow, manual measurements. The team plans to test the device at partner clinics in countries like Malawi, Mozambique, Uganda, and Kenya and improve the system based on real-world use.

Why it matters

Potential benefit: If successful, this could give more accurate, objective measurements of lesion size so treatments can be timed better and unnecessary chemotherapy exposure reduced.

How similar studies have gone: 3D imaging and AI have shown promise for measuring other skin conditions, but using the portable SkinScan3D specifically for Kaposi sarcoma in East Africa is a new application.

Where this research is happening

  • Washington University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Odeny, Thomas — Washington University
  • Study coordinator: Odeny, Thomas

Related research

Other NIH-funded projects on the same topics.

  • Precision 3D Imaging to Monitor Kaposi Sarcoma (KS) with SkinScan3D

    A new portable 3D imaging tool called SkinScan3D will help doctors measure KS skin lesions more accurately and quickly, especially in people living with HIV.

    NIH research Washington University · Saint Louis, United States · NIH-11535366

  • Precision 3D Imaging to Track Kaposi Sarcoma (KS) with SkinScan3D

    A new 3D imaging tool called SkinScan3D helps doctors monitor Kaposi sarcoma lesions more accurately and quickly, especially in settings with high KS burden like East Africa and in U.S. clinics with HIV patients.

    NIH research Washington University · Saint Louis, United States · NIH-11535365

  • Kaposi Sarcoma care and research in Africa during ART era

    A collaborative program to better understand and improve diagnosis, treatment, and prevention of Kaposi sarcoma for people living with HIV in Zambia and Tanzania.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11535231

  • Kaposi Sarcoma in Africa: ART Era Research Network

    A collaborative program in Africa and the United States will study Kaposi sarcoma in people living with HIV on ART to improve diagnosis, treatment, and prevention.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11535230

  • Kaposi Sarcoma in Africa in the ART Era

    This grant supports research to improve how Kaposi sarcoma is detected, treated, and understood in people living with HIV in Zambia and Tanzania during ART, with collaboration between African hospitals and a U.S. center.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11417959

  • Faster detection and connection to care for people with HIV who develop Kaposi sarcoma in East Africa

    This project aims to speed up finding people with HIV diagnosed with Kaposi sarcoma in East Africa and help them get linked to care more quickly.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11416376

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.