NIH-funded research U01 cooperative agreement

Precision 3D Imaging to Track Kaposi Sarcoma (KS) with SkinScan3D

Official title: PRecision IMaging to Evaluate Kaposi Sarcoma (PRIME-KS)

Funded at Washington University · NIH-11535365 · Data updated 2026-11-12

A new 3D imaging tool called SkinScan3D helps doctors monitor Kaposi sarcoma lesions more accurately and quickly, especially in settings with high KS burden like East Africa and in U.S. clinics with HIV patients.

More Sarcoma research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionWashington University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startAugust 7, 2024
Project endJuly 31, 2029
Funding year2026
Award (this year)$122,208
NIH project number3U01CA292765-03S1
Project IDNIH-11535365 on NIH RePORTER

Who could benefit from this research

Could help

Adults with Kaposi sarcoma who are receiving care in participating clinics, including settings with high KS burden.

Less likely to help

Patients with KS in settings not equipped to implement 3D imaging or where lesions are not accessible to surface imaging.

What this research studies

This grant tests a portable, affordable 3D imaging system to measure KS skin lesions in height and volume, aiming to replace tedious manual measurements. The approach pairs liquid lens imaging with artificial intelligence to produce reliable, objective lesion data during routine care. Conducted at Washington University with sites in regions with higher KS prevalence, the study will compare SkinScan3D measurements to current visual and manual methods. If successful, the tool could shorten treatment decisions, reduce unnecessary chemotherapy exposure, and speed up evidence generation for KS care in diverse settings.

Why it matters

Potential benefit: If successful, SkinScan3D could lead to faster, more accurate KS monitoring and better-informed treatment decisions for patients.

How similar studies have gone: Prior imaging innovations with 3D modalities have shown promise in improving lesion assessment, but this project applies a novel, portable AI-powered 3D approach to KS.

Where this research is happening

  • Washington University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Odeny, Thomas — Washington University
  • Study coordinator: Odeny, Thomas

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.