NIH-funded research NIH-funded research

Improving care and understanding of Kaposi sarcoma in Zambia and Tanzania

Official title: Kaposi Sarcoma in the Era of ART in Africa Program (KEAAP)

Funded at Lsu Health Sciences Center · NIH-11184252 · Data updated 2026-11-12

Researchers are partnering with hospitals in Zambia, Tanzania, and the United States to improve diagnosis, treatment, and prevention of Kaposi sarcoma for people living with HIV.

More Sarcoma research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLsu Health Sciences Center
NIH-funded
Lab location1 site (New Orleans, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2025
Award (this year)$390,617
NIH project number5U54CA277846-03
Project IDNIH-11184252 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are people living with HIV in Zambia or Tanzania who have suspected or confirmed Kaposi sarcoma or who receive care at the participating cancer hospitals.

Less likely to help

People who do not live in the participating regions, do not have HIV, or do not have Kaposi sarcoma are unlikely to directly benefit from this program.

What this research studies

This program brings together cancer hospitals in Zambia and Tanzania with LSU Health Sciences Center-New Orleans to study Kaposi sarcoma in the era of antiretroviral therapy. Teams will connect clinical care with laboratory studies to learn how KS develops, how the immune system responds, and how treatments influence outcomes. The program also strengthens local cancer research and treatment capacity so hospitals can diagnose and manage KS more effectively. Patients at participating sites may be invited to join observational studies, contribute tissue or blood samples, and access improved care pathways.

Why it matters

Potential benefit: If successful, this work could lead to earlier detection, better treatments, and fewer deaths from Kaposi sarcoma among people with HIV in sub-Saharan Africa.

How similar studies have gone: Wider rollout of antiretroviral therapy has reduced some Kaposi sarcoma burden, but coordinated research networks and capacity-building efforts like this are less common and aim to fill remaining gaps.

Where this research is happening

  • Lsu Health Sciences Center
    New Orleans, United States
    Active

Researchers

  • Principal investigator: Wood, Charles — Lsu Health Sciences Center
  • Study coordinator: Wood, Charles

Related research

Other NIH-funded projects on the same topics.

  • Precision 3D Imaging to Monitor Kaposi Sarcoma (KS) with SkinScan3D

    A new portable 3D imaging tool called SkinScan3D will help doctors measure KS skin lesions more accurately and quickly, especially in people living with HIV.

    NIH research Washington University · Saint Louis, United States · NIH-11535366

  • Precision 3D Imaging to Track Kaposi Sarcoma (KS) with SkinScan3D

    A new 3D imaging tool called SkinScan3D helps doctors monitor Kaposi sarcoma lesions more accurately and quickly, especially in settings with high KS burden like East Africa and in U.S. clinics with HIV patients.

    NIH research Washington University · Saint Louis, United States · NIH-11535365

  • Kaposi Sarcoma care and research in Africa during ART era

    A collaborative program to better understand and improve diagnosis, treatment, and prevention of Kaposi sarcoma for people living with HIV in Zambia and Tanzania.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11535231

  • Kaposi Sarcoma in Africa: ART Era Research Network

    A collaborative program in Africa and the United States will study Kaposi sarcoma in people living with HIV on ART to improve diagnosis, treatment, and prevention.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11535230

  • Kaposi Sarcoma in Africa in the ART Era

    This grant supports research to improve how Kaposi sarcoma is detected, treated, and understood in people living with HIV in Zambia and Tanzania during ART, with collaboration between African hospitals and a U.S. center.

    NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11417959

  • Faster detection and connection to care for people with HIV who develop Kaposi sarcoma in East Africa

    This project aims to speed up finding people with HIV diagnosed with Kaposi sarcoma in East Africa and help them get linked to care more quickly.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11416376

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.