New ways to screen and predict outcomes for HIV-related cancers in Malawi and South Africa
Official title: Innovations for screening and prognosis in HIV+ cancers including Kaposi sarcoma, cervical cancer, and lymphoma in Malawi and South Africa
Funded at Univ of North Carolina Chapel Hill · NIH-10891536 · Data updated 2026-11-12
This study is working to find better ways to detect and understand cancers linked to HIV, like Kaposi sarcoma, cervical cancer, and lymphoma, in Malawi and South Africa, so that people living with HIV can get the help they need more effectively.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | August 13, 2020 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $1,094,228 |
| NIH project number | 5U54CA254564-05 |
| Project ID | NIH-10891536 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV who are at risk for or diagnosed with Kaposi sarcoma, cervical cancer, or lymphoma.
✕Less likely to help
Patients who do not have HIV or are not at risk for the specified cancers may not benefit from this research.
What this research studies
This research focuses on improving the screening and prognosis of HIV-associated cancers, specifically Kaposi sarcoma, cervical cancer, and lymphoma, in Malawi and South Africa. It aims to establish the UNC-Malawi-South Africa Cancer Consortium to enhance research capacity and conduct impactful studies in these regions. By leveraging existing collaborations and infrastructure, the project seeks to address the significant cancer burden faced by individuals living with HIV. The approach includes innovative methods tailored to the unique challenges of these populations.
Why it matters
Potential benefit: If successful, this research could lead to better screening techniques and prognostic tools for HIV-related cancers, ultimately improving patient outcomes.
How similar studies have gone: Previous research has shown promise in improving outcomes for HIV-related cancers, indicating that this approach could build on established findings.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Damania, Blossom a — Univ of North Carolina Chapel Hill
- Study coordinator: Damania, Blossom a
Related research
Other NIH-funded projects on the same topics.
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Targeted therapies for HIV-related Kaposi sarcoma and lymphoma
A patient-focused look at new targets and drug combinations to treat Kaposi sarcoma and AIDS-related lymphomas in people living with HIV.
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New treatments for Kaposi sarcoma and lymphoma in people with HIV
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Precision 3D Imaging to Monitor Kaposi Sarcoma (KS) with SkinScan3D
A new portable 3D imaging tool called SkinScan3D will help doctors measure KS skin lesions more accurately and quickly, especially in people living with HIV.
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Precision 3D Imaging to Track Kaposi Sarcoma (KS) with SkinScan3D
A new 3D imaging tool called SkinScan3D helps doctors monitor Kaposi sarcoma lesions more accurately and quickly, especially in settings with high KS burden like East Africa and in U.S. clinics with HIV patients.
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Kaposi Sarcoma care and research in Africa during ART era
A collaborative program to better understand and improve diagnosis, treatment, and prevention of Kaposi sarcoma for people living with HIV in Zambia and Tanzania.
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Kaposi Sarcoma in Africa: ART Era Research Network
A collaborative program in Africa and the United States will study Kaposi sarcoma in people living with HIV on ART to improve diagnosis, treatment, and prevention.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.